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Discovered one of the mechanism that influences aggressiveness in Ewing’s Sarcoma

Caveolin-1 participates in the formation of new blood vessels around the tumor, facilitating growth and proliferation The finding opens the door to the investigation of new therapies against this childhood cancer Angiogenesis and solid tumors Future therapies Article’s reference EphA2-induced angiogenesis in Ewing sarcoma celles works through bGFG production and is dependent on caveolin-1.

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Improvement in the diagnosis of testosterone deficiency syndrome in men allows an early treatment

The testosterone deficiency syndrome (TDS) is a clinical and biochemical syndrome associated with advancing age. It Is produced by a gradual drop in testosterone levels which affects the sexual sphere, leading to a decrease in sexual desire and morning erections, as well as decreasing the quality and frequency of erections. It can also affect the […]

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IDIBELL’s researcher Eva González-Suárez awarded with a grant from Susan G. Komen® to investigate new therapies in breast cancer

The research group leader in transformation and metastasis of the Bellvitge Biomedical Research Institute (IDIBELL), Eva González-Suárez, has been awarded with a research grant from Susan G. Komen®, the world’s leading breast cancer organization. The project is funded with 450 000 dollars for the next three years. Komen was founded in 1982 with the goal […]

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The epigenome differentiates the different human populations

What makes us different? What differentiates us from our neighbors, our friends or strangers from distant countries? For years we know that there are genetic differences among different human populations that contribute to their appearance and to a different susceptibility to disease. These small genetic differences between healthy individuals are called “polymorphisms”. The group of […]

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Annual Report 2012

In 2012 the IDIBELL has positioned itself as a reference in healthcare innovation having driven a system of innovative public procurement in the field of health, in which the contractor and the bidder share the risks of the application of a new technology. The model, common in other countries, leverages the high purchasing capacity of […]

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Patented a molecule that opens the door to develop new drugs against immune rejection

Researchers of the research group in Human Molecular Genetics of the Biomedical Research Institute of Bellvitge (IDIBELL), led by researcher Mercedes Pérez, have patented a peptide (a molecule consisting of a sequence of amino acids) that inhibits the immune response activated by the enzyme calcineurin which could serve to develop new more specific immunosuppressive drugs […]

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Learning a language depends on good connection between regions of the left hemisphere of the brain

Language is a uniquely human ability. The average person’s vocabulary consists of about thirty thousand words, although there are individual differences in the ability to learn a new language. It has long been believed that language acquisition depends on the integration of the information between motor and auditory representation of words in the brain, but […]

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Discovered a future therapeutic target for lung cancer treatment

One of the goals of research in cancer genetics and molecular biology is to get an “on demand” treatment, ie studying the alterations in a tumor can decide which the best drug is: maximum effect and minimal toxicity. Two recent examples in this field are the findings that lung cancer patients carrying mutations in EGFR […]

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Dual effect of an antibiotic opens the door to find a drug against a very aggressive childhood cancer

An antibiotic that is currently used in veterinary named thiostrepton inhibits two transcription factors related to the appearance of Ewing’s sarcoma, a cancer that affects children and young people. It is a proof of concept done in cell lines and in mice. Although it is expected that the same molecule cannot be used directly in […]

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