Infections and Cancer

Summary

The Infections and Cancer group focusses on the fight between viruses and hosts, from an evolutionary perspective: the antiviral mechanisms which animals have developed and the antiviral strategies which have contributed to virus selection. It researches the connection between infection and cancer, as exemplified by the human papilloma virus (HPV).

925 Publications

Strategic lines

Human papilloma virus (HPV) and genital cancer.
HPV and cancer of the oesophagus, oral cavity, skin, vagina, vulva, penis and anus.
Hepatotropic viruses (hepatitis B and C virus – HBV, HCV) and cancer of the liver.
Trials on HPV vaccination and intervention studies on cancer prevention.
Infectious aetiology of malignant lymphomas.
WHO/ICO HPV and Cervical Cancer Information Centre.
Development of logistics instruments for coordination and diffusion of information regarding viruses and cancer.
Screening and prevention of genital cancer.
Evaluation of virus detection technologies.
Financial modelling and evaluation of cancer prevention measures.

Selected Publications

Population-level impact of human papillomavirus vaccination

Brotons M, Bruni L.

Lancet.2020, doi: 10.1016/S0140-6736(19)33153-8

Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis

Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, Bray F

Lancet Global Health. 2020, doi: 10.1016/S2214-109X(19)30482-6

VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma

Lorenzo-Martin, L. Francisco; Fernandez-Parejo, Natalia; Menacho-Marquez, Mauricio; Rodriguez-Fdez, Sonia; Robles-Valero, Javier; Zumalave, Sonia; Fabbiano, Salvatore; Pascual, Gloria; Garcia-Pedrero, Juana M.; Abad, Antonio; Garcia-Macias, Maria C.; Gonzalez, Nazareno; Lorenzano-Menna, Pablo; Pavon, Miguel A.; Gonzalez-Sarmiento, Rogelio; Segrelles, Carmen; Paramio, Jesus M.; Tubio, Jose M. C.; Rodrigo, Juan P.; Benitah, Salvador A.; Cuadrado, Myriam; Bustelo, Xose R.

NATURE COMMUNICATIONS. 2020, doi: 10.1038/s41467-020-18524-3

Role of Human Papillomavirus Infection in Head and Neck Cancer in Italy: The HPV-AHEAD Study

Tagliabue, Marta; Mena, Marisa; Maffini, Fausto; Gheit, Tarik; Blasco, Beatriz Quiros; Holzinger, Dana; Tous, Sara; Scelsi, Daniele; Riva, Debora; Grosso, Enrica; Chu, Francesco; Lucas, Eric; Ridder, Ruediger; Rrehm, Susanne; Bogers, Johannes Paul; Lepanto, Daniela; Rubio, Belen Lloveras; Kumar, Rekha Vijay; Gangane, Nitin; Clavero, Omar; Pawlita, Michael; Anantharaman, Devasena; Pillai, Madhavan Radhakrishna; Brennan, Paul; Sankaranarayanan, Rengaswamy; Arbyn, Marc; Lombardi, Francesca; Taberna, Miren; Gandini, Sara; Chiesa, Fausto; Ansarin, Mohssen; Alemany, Laia; Tommasino, Massimo; Chiocca, Susanna

CANCERS. 2020. doi: 10.3390/cancers12123567

Cervical screening: ESGO-EFC position paper of the European Society of Gynaecologic Oncology (ESGO) and the European Federation of Colposcopy (EFC)

Kyrgiou, Maria; Arbyn, Marc; Bergeron, Christine; Bosch, F. Xavier; Dillner, Joakim; Jit, Mark; Kim, Jane; Poljak, Mario; Nieminen, Pekka; Sasieni, Peter; Kesic, Vesna; Cuzick, Jack; Gultekin, Murat

BRITISH JOURNAL OF CANCER. 2020, doi: 10.1038/s41416-020-0920-9

Selected Projects