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Xenograft Animal Models Recapitulate Genetic Behavior of Original Human Tumors

Researchers from IDIBELL and ICO have participated in a multicenter study, published in Nature Genetics, which shows that the implantation of human tumors in nude mice does not lead to additional DNA changes.

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Aptadel, the new IDIBELL’s spinoff

Aptadel Therapeutics is a preclinical company co-founded by IDIBELL focused on developing a new platform for targeted therapy against cancer.

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Cancer’s Key Vulnerabilities found by Big Data Analysis

The study lead by Columbia University, in collaboration with IDIBELL and ICO, analysed thousands of tumours. They found that the key genetic programs necessary for the survival of cancer cells are controlled by only 24 modules, each one comprising only a handful of Master Regulators proteins working in concert.

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2020 highlights!

2020 is coming to its end, a year with great difficulties and challenges. However, this year, more than ever, we have proved the strength of our research.

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Combined therapy could be a solution for EGFR inhibitor-resistant skin squamous cell cancers

A team from IDIBELL has deciphered the molecular mechanisms responsible for resistance to EGFR inhibitors and offers new therapeutic strategies.

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Iron treatment reduces the risk of hospitalization in people with heart deficiencies

Results, released simultaneously at the American Heart Association (AHA) 2020 virtual conference and in the journal The Lancet, show that patients who received the iron supplement were 26% less likely to be readmitted to the hospital for heart failure compared to the control group.

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Spain is one of the most permissive states with the tobacco industry interference in tobacco control

This is one of the results indicated by the latest report of the ‘Global Tobacco Industry Interference Index’ published this November and in which Spain obtains a score that places it behind 35 countries out of the 57 analyzed.

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A multicenter approach improves genetic variants classification of a cancer predisposition gene

The correct classification of genetic variants can help in the early diagnosis and personalized treatment of cancer in patients who carry this gene.

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