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An international study allows a better prediction of the risk of hereditary cancer

The paper analyzes the role of different genetic variants involved in Lynch syndrome , an inherited disease that increases the risk of various tumors The study is published in the journal Nature Genetics and has had the participation of Gabriel Capellá and Marta Pineda, form the Hereditary Cancer Program at the Catalan Institute of Oncology […]

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Researchers discover a tumor suppressor gene in a very aggressive lung cancer

The Genes and Cancer Group at the Cancer Epigenetics and Biology Program of the IDIBELL has found that the MAX gene, which encodes a partner of the MYC oncogene, is genetically inactivated in small cell lung cancer. Reconstitution of MAX significantly reduced cell growth in the MAX-deficient cancer cell lines. These findings show that MAX […]

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Researchers propose an alternative therapy to fight testicular cancer refractory to chemotherapy

Researchers at Tumor angiogenesis group at Bellvitge Biomedical Institute of Research (IDIBELL) and the Catalan Institute of Oncology (ICO) led by Francesc Viñals have published a study in the journal Clinical Cancer Research where they propose an alternative treatment to cisplatin resistant testicular cancer patients . 90 % cure rate of testicular tumors Testicular tumor […]

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A free web application developed by the ICO-IDIBELL enables data analysis new generation sequencing

The last two years have seen a significant change in the field of genetic diagnosis , mainly due to the application of technologies next generation sequencing (NGS , next generation sequencing) in medium-capacity devices. The development of these instruments, together with the launch of commercial kits to study a limited number of genes, has allowed […]

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Horizon 2020 launched with €15 billion over first two years

The European Commission has for the first time presented calls for projects under Horizon 2020, the European Union’s €80 billion research and innovation programme. Worth more than €15 billion over the first two years, the funding is intended to help boost Europe’s knowledge-driven economy, and tackle issues that will make a difference in people’s lives. […]

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Keeping growth in check

Researchers from the Laboratory of Cancer Metabolism (LCM) led by George Thomas at the Bellvitge Biomedical Research Institute (IDIBELL), the Catalan Institute of Oncology (ICO) and the Division of Hematology/ Oncology, University of Cincinnati, have shown that loss of either one of two tumor suppressors, ribosomal proteins RPL5 or RPL11, fail to induce cell-cycle arrest, […]

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Researchers describe the key role of a protein in the segregation of genetic material during cell division

Researchers at the Cell Cycle Research Group of the Bellvitge Institute of Biomedical Research (IDIBELL) led by Ethel Queralt have reported in the journal PLoS Genetics an article which delve into the regulator mechanisms of mitosis, a key stage of the cell-cycle for the correct transmision of genetic information from parents to sons. Cell-cycle Cells […]

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