News
Discovered a future therapeutic target for lung cancer treatment
One of the goals of research in cancer genetics and molecular biology is to get an “on demand” treatment, ie studying the alterations in a tumor can decide which the best drug is: maximum effect and minimal toxicity. Two recent examples in this field are the findings that lung cancer patients carrying mutations in EGFR […]
Dual effect of an antibiotic opens the door to find a drug against a very aggressive childhood cancer
An antibiotic that is currently used in veterinary named thiostrepton inhibits two transcription factors related to the appearance of Ewing’s sarcoma, a cancer that affects children and young people. It is a proof of concept done in cell lines and in mice. Although it is expected that the same molecule cannot be used directly in […]
The human papilloma virus multiplies the risk of oral cancer
HPV 16, one of the more aggressive types of HPV is present in over 30% of patients with cancers of the oropharynx and in less than 1% of healthy people HPV antibodies in blood HPV, responsible for more than 5% of cancers Early detection for better prognosis
Adults with eating disorders have a poorer prognosis if they suffer hyperactivity
A study with 191 patients reveal that symptoms of hyperactivity due to the deficit of attention and hyperactivity disorder (ADHD) are associated with more impulsivity and more severity, and probably a worse prognosis in patients with eating disorders. ADHD in adults is poorly investigated and, although several studies have reported associations between this disorder and […]
Brain epigenome changes from birth to adolescence
Experience of parents with their children and teachers with their students demonstrate how kids change their behaviours and knowledge from childhood to adolescence. Until now, little was known of the causes that could lead to these changes. Today, an article published in Science in collaboration with the group of Manel Esteller, Director of Epigenetics and […]
Discovered the role of noncoding 5S rRNA in protecting the p53 tumor suppressor gene
Researchers of the Cancer Metabolism group at the Bellvitge Biomedical Research Institute (IDIBELL), Catalan Oncology Institute (ICO) and the Division of Hematology-Oncology of the University of Cincinnati, led by George Thomas, have discovered a role for ribosomal 5S RNA in the formation of a complex that regulates the stability of p53. Normally, p53 prevents healthy […]
Roderic Guigo: ”We do not work only to know the genome sequence but to understand how DNA works in different conditions”
The head of bioinformatics and genomics laboratory of the Centre for Genomic Regulation in Barcelona (CRG), Roderic Guigo, explained the latest developments of the ENCODE project at a conference framed in IDIBELL seminar series on 14 June. In 2003, the ENCODE project begun with the aim of knowing the human genome. The project has grown […]
Six students will live summer at IDIBELL
Six students will have the opportunity to complete their formation in one of the IDIBELL research groups. The training will last three months, from July to September. The students have finished the last course of a biomedical bachelor’s program. The Scientific Direction of IDIBELL has evaluated the applications received and has announced the awarded of […]
Mutua Madrileña Foundation funds IDIBELL and ICO project to improve molecular diagnosis of Lynch syndrome
The Fundación Mutua Madrileña, in its 10th Call for Aids to Research, has selected a project to improve the diagnosis of Lynch syndrome led by researcher Marta Pineda, from the Hereditary Cancer research group of the Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan Institute of Oncology (ICO). The aid is provided with 33,000 euros […]