Infections and Cancer

Summary

The Infections and Cancer group focusses on the fight between viruses and hosts, from an evolutionary perspective: the antiviral mechanisms which animals have developed and the antiviral strategies which have contributed to virus selection. It researches the connection between infection and cancer, as exemplified by the human papilloma virus (HPV).

925 Publications

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Strategic lines
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Human papilloma virus (HPV) and genital cancer.
HPV and cancer of the oesophagus, oral cavity, skin, vagina, vulva, penis and anus.
Hepatotropic viruses (hepatitis B and C virus - HBV, HCV) and cancer of the liver.
Trials on HPV vaccination and intervention studies on cancer prevention.
Infectious aetiology of malignant lymphomas.
WHO/ICO HPV and Cervical Cancer Information Centre.
Development of logistics instruments for coordination and diffusion of information regarding viruses and cancer.
Screening and prevention of genital cancer.
Evaluation of virus detection technologies.
Financial modelling and evaluation of cancer prevention measures.
Selected Publications
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Kolijn PMM, Saberi Hosnijeh F, Späth F, Hengeveld PJ, Agathangelidis A, Saleh M, Casabonne D, Benavente Y, Jerkeman M, Agudo A, Barricarte A, Besson C, Sánchez MJ, Chirlaque MD, Masala G, Sacerdote C, Grioni S, Schluze M, Nieters A, Engelfriet P, Hultdin M, McKay JD, Vermeulen RCH, Langerak AW. HIGH-RISK SUBTYPES OF CHRONIC LYMPHOCYTIC LEUKEMIA ARE DETECTABLE AS EARLY AS 16 YEARS PRIOR TO DIAGNOSIS. Blood. 2022;139(10):1557-1563. doi:10.1182/blood.2021012890.

Watson Jones D, Changalucha J, Whitworth H, Pinto L, Mutani P, Indangasi J, Kemp T, Hashim R, Kamala B, Wiggins R, Songoro T, Connor N, Mbwanji G, Pavon MA, Lowe B, Mmbando D, Kapiga S, Mayaud P, de Sanjosé S, Dillner J, Hayes RJ, Lacey CJ, Baisley K. Immunogenicity and safety of one-dose human papillomavirus vaccine compared with two or three doses in Tanzanian girls (DoRIS): an open-label, randomised, non-inferiority trial. Lancet Glob. Health. 2022;10(10):1473-1484. doi:10.1016/S2214-109X(22)00309-6.

Herzog C, Marín F, Jones A, Evans I, Reisel D, Redl E, Schreiberhuber L, Paytubi S, Pelegrina B, Carmona Á, Peremiquel Trillas P, Frias Gomez J, Pineda M, Brunet J, Ponce J, Matias Guiu X, de Sanjosé S, Alemany L, Olaitan A, Wong M, Jurkovic D, Crosbie EJ, Rosenthal AN, Bjørge L, Zikan M, Dostalek L, Cibula D, Sundström K, Dillner J, Costas L, Widschwendter M. A Simple Cervicovaginal Epigenetic Test for Screening and Rapid Triage of Women With Suspected Endometrial Cancer: Validation in Several Cohort and Case/Control Sets. J. Clin. Oncol. 2022;40(33):3828-doi:10.1200/JCO.22.00266.

Paytubi S, Benavente Y, Montoliu A, Binefa G, Brotons M, Ibanez R, Ochoa C, Peremiquel Trillas P, Serrano B, Travier N, Alemany L, Costas L. Everything causes cancer? Beliefs and attitudes towards cancer prevention among anti-vaxxers, flat earthers, and reptilian conspiracists: online cross sectional survey. BMJ-British Medical Journal. 2022;379doi:10.1136/bmj-2022-072561.

Bruni L, Serrano B, Roura E, Alemany L, Cowan M, Herrero R, Poljak M, Murillo R, Broutet N, Riley LM, de Sanjose S. Cervical cancer screening programmes and age-specific coverage estimates for 202 countries and territories worldwide: a review and synthetic analysis. Lancet Glob. Health. 2022;10(8):1115-1127.

Selected Projects

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CEE21039. PERCH: PartnERship to Contrast HPV. COMISSIÓ EUROPEA. Budget: 409468,03. 2022-2025. PI: Brotons Agulló, Maria.

MCI22005. WOMEC ADVANCED : NUEVAS APROXIMACIONES PARA EL DIAGNÓSTICO DE CÁNCER DE ENDOMETRIO. Ministerio de Ciencia e Innovación. Budget: 194288. 2022-2025. PI: Costas Caudet, Laura.

19CEE002. HEADSpAcE: Translational studies of HEAD and neck cancer in South America and Europe. COMISSIÓ EUROPEA. Budget: 249985. 2019-2023. PI: Alemany Vilches, Laia.

PNJ22019. Reduction of VIral InFectivity and Transmission in HPV positive women before and after vaccination with GARDASIL-9. The effect in oral and anal body fluids and after 1- or 2- vaccine doses (RIFT-HPV II). MERCK SHARP & DOHME ESPAÑA S.A.. Budget: 140478,25. 2021-9999. PI: Bosch José, Francesc Xavier.

FIS21057. Human papillomavirus protection index (HPV-PI). Instituto de Salud Carlos III (ISCIII). Budget: 47190. 2022-2024. PI: Bruni Coccoz, Laia.

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