Cellular and molecular neurobiology

Summary

The Cellular and Molecular Neurobiology group investigates the molecular mechanisms that control neurotransmission. We are interested in all aspects related to the cell biology of synapses, paying particular attention to events related to the trafficking of synaptic vesicles. The group has its origins in the use of toxins, particularly neurotoxins, to study cellular and tissular processes related to regulated secretion (neurotransmitters, hormones). Our findings have a broad translational interest and are particullarly relevant to synaptopathies, which are diseases that cause synaptic disfunctions and include, for example, autism spectrum disorder, schizophrenia or many neurodegenerative diseases.

349 Publications

Strategic lines

Selected Publications

Nadal,M;Anton,R;Dorca Arevalo,J;Estebanez Perpina,E;Tizzano,EF;Fuentes Prior,P, Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts, Protein Sci., 2023;32(4):doi:10.1002/pro.4553,
Möller Parera,I;Miguel,M;Blasi,J;Piccaso,R;Hammer,HB;Ortiz Sagrista,J;Zaottini,F et al, Ultrasound assessment of degenerative muscle sarcopenia: the University of Barcelona ultrasound scoring system for sarcopenia., RMD Open, 2023;9(1):doi:10.1136/rmdopen-2022-002779
Velasco,CD;Santarella Mellwig,R;Schorb,M;Gao,L;Thorn Seshold,O;Llobet,A, Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro, Commun. Biol., 2023;6(1):488-488, doi:10.1038/s42003-023-04779-1
Coronel,L;Mandl,P;Miguel Párez,M;Blasi,J;D'Agostino,MA;Martinoli,C;Bong,DA et al, Characterization of digital annular pulleys and their entheses: an ultrasonographic study with anatomical and histological correlations, RHEUMATOLOGY 2023; doi:10.1093/rheumatology/kead614
Bustos Salgado,P;Domínguez Villegas,V;Andrade Carrera,B; Mallandrich,M; Calpena,A; Domènech,O; Martínez Ruiz,S et al, PLGA Nanoparticles Containing Natural Flavanones for Ocular Inflammation, Pharmaceutics, 2023;15(12):doi:10.3390/pharmaceutics15122752,