July 2020

The study of lysosomal function during cell division enables the identification of a new biomarker for chromosomal instability

By studying the role of lysosomes in mitosis, an IDIBELL and UB group discovers that alterations in the separation of chromosomes cause a detectable nucleus morphology once mitosis has finished. This morphology would be useful to identify cells that have chromosomal instability inherent in cancer cells.

The combination of four drugs at low doses is more effective and less toxic in the treatment of a lung cancer type

The study, published in the Nature Communications journal, and led by the Netherlands Cancer Institute (NKI), has had the collaboration of researchers from IDIBELL/ICO and HUB.
This study demonstrates the beneficial effect of treatment with a cocktail drug at low doses to block a single signaling pathway in a lung cancer type.

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