The appointment coincides with the constitution of the Research Integrity Committee (CIR), chaired by the Ombudsperson and including different members of the IDIBELL research community, and the update of the “Guide to Good Practices in Research in Health Sciences”.
By studying the role of lysosomes in mitosis, an IDIBELL and UB group discovers that alterations in the separation of chromosomes cause a detectable nucleus morphology once mitosis has finished. This morphology would be useful to identify cells that have chromosomal instability inherent in cancer cells.
The study, published in the Nature Communications journal, and led by the Netherlands Cancer Institute (NKI), has had the collaboration of researchers from IDIBELL/ICO and HUB.
This study demonstrates the beneficial effect of treatment with a cocktail drug at low doses to block a single signaling pathway in a lung cancer type.