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A mouse model was used to determine the personalized treatment for a cancer patient

A team from IDIBELL and ICO, using a mouse orthotopic model, conducted a real-time personalized oncology study to test the best therapeutic option to treat a type of relapse sarcoma.

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Common immune characteristics found in lung metastases to target future treatments

Lung metastatic tumours have common immune properties, regardless of the origin of the primary tumour.
These results suggest new approximations and contemplate the development of new immunotherapy treatments.

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A clinical trial coordinated by IDIBELL validates a less aggressive surgery for lower rectal cancer

The study has been published by the JAMA Surgery journal, the most prestigious in the world in its field, and has been led by Dr Sebastiano Biondo, from IDIBELL and the Bellvitge University Hospital.

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The study of lysosomal function during cell division enables the identification of a new biomarker for chromosomal instability

By studying the role of lysosomes in mitosis, an IDIBELL and UB group discovers that alterations in the separation of chromosomes cause a detectable nucleus morphology once mitosis has finished. This morphology would be useful to identify cells that have chromosomal instability inherent in cancer cells.

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A study proposes a new approach for the identification of a syndrome of predisposition to childhood cancer

Patients with this syndrome have more mutations in the microsatellite regions of the genome. The detection of these mutations improves the diagnosis and therapeutic management of patients.

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The combination of four drugs at low doses is more effective and less toxic in the treatment of a lung cancer type

The study, published in the Nature Communications journal, and led by the Netherlands Cancer Institute (NKI), has had the collaboration of researchers from IDIBELL/ICO and HUB.
This study demonstrates the beneficial effect of treatment with a cocktail drug at low doses to block a single signaling pathway in a lung cancer type.

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IDIBELL and Bellvitge Institute educational Tandem closes the course with a COVID-19 project

The educational Tandem, formed by the Bellvitge Institute and IDIBELL has closed the 2019-2020 academic year launching a challenge for 3rd ESO students: researching the new coronavirus. The emergence of COVID-19 and the situation of confinement motivated a project that aimed to promote knowledge and research on different aspects related to viruses, the human body […]

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Identified genes that predispose to cancer by impairing the protective function of the immune system

The study shows that the involvement of certain genes that predispose to cancer also affects the immune system, which could facilitate tumor growth.
In the specific case of breast cancer, the involvement of the SH2B3 gene, corresponding to a lymphocyte protein, increases the predisposition to develop cancer.

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