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José Luis Hernández: ”We have designed two antibodies that block S100 proteins and we’ve observed that slow tumors growth”

The laboratory of José Luis Hernández at the Biomed division, LEITAT Technology Center of Barcelona works in the clinical application of two antibodies designed by them to block proliferative function of extracellular S100 proteins. Hernandez explained his research on April 26 at a conference framed at IDIBELL seminars cycle. “We designed two antibodies that block […]

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IDIBELL license to Minoryx a patent of a product to treat a rare neurodegenerative disease

IDIBELL has signed a licensing agreement with the Catalan biotechnology company Minoryx of a patent for the treatment of X-linked adrenoleukodystrophy, a rare serious neurodegenerative disease, which has no effective treatment. The Neurometabolic Diseases group led by ICREA researcher Aurora Pujol, has developed an animal model to study this disease. Studies using this model have […]

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‘Dark genome’ is involved in Rett Syndrome

Researchers at the Epigenetics and Cancer Biology Program at IDIBELL led by Manel Esteller, ICREA researcher and professor of genetics at the University of Barcelona, have described alterations in noncoding long chain RNA sequences (lncRNA) in Rett syndrome. These molecules act as supervisor agents responsible of ‘switch on’ or ‘switch off’ other genes in our […]

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Cedric Notredame: “We want to understand under what pressure evolves long noncoding RNA”

According to the ENCODE‘s latest update in the human genome there are about 10,000 long sequences of RNA that do not code for any protein. Cedric Notredame’s lab at the Center for genomic Regulation (CRG) tries to detect these molecules not only in humans but also in other species to understand their functionality. Cedric Notredame […]

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Piero Crespo: “We look for site-specific inhibitors and that block protein-protein interactions”

The field of study of Piero Crespo at the Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC) is the regulation of Ras-ERK signals. On April 19, explained the latest developments of their research at a conference framed in IDIBELL seminar series. His work focuses on the study of the mechanisms of Ras regulation in particular […]

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High school students discover how research at IDIBELL is

On April 16th science students of the French School of Barcelona visited the IDIBELL to see firsthand how a biomedical research center works. Researchers of the neurometabolic diseases group explained to students the research of a rare disease, the X-linked adrenoleukodistrophy, from basic research, to the investigation with animal models and clinical trial patients. The […]

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Identified as responsible for breast and ovarian hereditary cancer three BRCA1 mutations

Researchers of the hereditary cancer research group at the Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan Institute of Oncology (ICO) conducted a functional and structural study of seven missense variants of the BRCA1 gene concluding that three of these variants are pathogenic, linked to the risk of suffering breast or ovarian cancer. The study […]

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Laura Valle awarded ‘young researcher in human genetics’

The researcher of the hereditary cancer group at IDIBELL, Laura Valle, has been awarded ‘young researcher in human genetics’ of the Spanish Association of Human Genetics (AEGH). The award was presented on April 12 in Madrid, under the XXVII Congress of the Association, which was held between 10 and 12 April. The award recognizes the […]

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Rui Benedito: ”We are developing new tools to dissect the molecular mechanisms of angiogenesis”

Researcher Rui Benedito of the National Center for Cardiovascular Research Carlos III (CNIC) Madrid explained his research on the regulation of angiogenesis through the Notch signalling pathway on April 5 at a conference cycle framed within IDIBELL seminars. Angiogenesis is the formation of new blood vessels from pre-existing vessels. Benedito studies this process that normally […]

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