Month: January 2021

Xenograft Animal Models Recapitulate Genetic Behavior of Original Human Tumors

Researchers from IDIBELL and ICO have participated in a multicenter study, published in Nature Genetics, which shows that the implantation of human tumors in nude mice does not lead to additional DNA changes.

Cancer’s Key Vulnerabilities found by Big Data Analysis

The study lead by Columbia University, in collaboration with IDIBELL and ICO, analysed thousands of tumours. They found that the key genetic programs necessary for the survival of cancer cells are controlled by only 24 modules, each one comprising only a handful of Master Regulators proteins working in concert.

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