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Joan Guinovart: ”We try to understand how manipulating glycogen metabolism we can improve health”

This is the aim of metabolic engineering laboratory and diabetes at the Institute for Research in Biomedicine of Barcelona (IRBB) led by the center director, Joan Guinovart. The researcher explained on 6 May in the framework of the seminars of IDIBELL how accumulation of glycogen may be beneficial in some tissues such as liver and harmful in cells such as neurons where it can be lethal.

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The University Hospital of Bellvitge, the first center in the world to perform a laparoscopic gastric plication robotic surgery

The Bellvitge University Hospital has organized on 2 and 3 May, the VIII International Course of Metabolic and Bariatric Laparoscopic Surgery with the assistance of national and international leading experts.

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Identified a gene responsible for a genetic disorder of myelin

In the study, published and selected as a featured article in the journal Cell Group The American Journal of Human Genetics, also have participated Albert Martinez, researcher at Institute for Research in Biomedicine (IRB Barcelona) and Virginia Nunes, professor at UB and IDIBELL researcher. More information: http://www.ub.edu/web/ub/ca/menu_eines/noticies/2011/05/009.html

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Proposed new strategies for treatment of cardiovascular disease in diabetics

U p to 40% of patients with diabetes do not respond to usual treatments A review article realized by researchers at IDIBELLabout the situation of antiplatelet therapy in acute coronary syndromes in patients with type 2 diabetes highlights the need for new potent therapies for this population at risk. Response to current drugs Article’s reference

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Agreement between IDIBELL and Vicente Ferrer Foundation to develop research activities

IDIBELL and Vicente Ferrer Foundation have signed a cooperation agreement to conduct common research activities. The framework agreement includes the exchange of research staff, organization of scientific events, the development of innovative health interventions and technology transfer activities, and the use of scientific facilities. The agreement includes a program to support predoctoral biomedicine students from India hosted by Vicente Ferrer Foundation in Andhra Pradesh region of India. The programme offers the possibility to obtain the PhD degree at IDIBELL facilities.

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Discovered a new mechanism which protects the genome under conditions of oxidative stress

Oxidative stress causes genomic instability and it could be involved in cancer emergence The role of sirtuins Article’s reference

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Molecule Nutlin-3a activates a signal inducing cell death and senescence in primary brain tumors

IDIBELL researchers at UB have tested this molecule antagonist of MDM2, a protein active in brain tumors New therapeutic targets Article reference

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Henning Walczak: ”We have all the mechanisms at our disposal to know the enemy and fight it”

The Walczak research group aims at understanding how the immune system specifically attacks the cancer and to uncover the mechanisms used by tumors to counteract these attacks. The researcher has explained his research in the TRAIL signaling pathway (TNF– related apoptosis-inducing ligand) to discover new therapeutic targets that can be combined with other drugs causing […]

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