News
BRG1 mutations confer resistance to hormones in lung cancer
Retinoic acid (vitamin A) and steroids are hormones found in our body that protect against oxidative stress, reduce inflammation and are involved in cellular differentiation processes. One of the characteristics of tumors is that their cells have lost the ability to differentiate; therefore these hormones have useful properties to prevent cancer. Currently, retinoic acid and […]
Xavier Bosch, Lilly Biomedical Research Award 2012
The researcher Xavier Bosch, head of the group on Viruses and Cancer at IDIBELL and Director of the Research in Cancer Epidemiology program at the Catalan Institute of Oncology (ICO), has been awarded the Lilly Foundation for Biomedical Research award 2012 in the category preclinical research. The Lilly Foundation has highlighted the contribution of Xavier […]
Nature Biotech calls ”signal of a new era in biomedical research” the BLUEPRINT project
Nature Biotech publishes in its latest issue an article about the European project Blueprint that was launched last October and aims to generate epigenomic maps of up to one hundred different types of blood cells to help researchers understand how the epigenome influences health and disease. The Cancer Epigenetics and Biology Program of IDIBELL, led […]
Peter Ten Dijke: “TGF-beta receptors may be therapeutic targets in treatments to prevent metastasis
The study of the molecular mechanisms that regulate the signaling pathways of transforming growth factor (TGF-beta) is the field of action of Peter Ten Djike and his research group at the University of Leiden, the Netherlands. Ten Djike explained their latest developments in a lecture in the seminar series IDIBELL on March 2. TGF-beta is […]
IDIBELL participates in a European project to detect and prevent type 2 diabetes
Researchers of the Epigenetics and Cancer Biology program at IDIBELL, led by Manel Esteller, participate in the European project DEXLIFE that aims research new ways to detect and prevent type 2 diabetes. The project funded with 5.5 million euros by the European Union within the 7th Framework Programme for Research and Development will take place […]
The loss of a protein makes ‘jump’ the tumor to the lymph node
Metastasis is responsible for 90% of deaths in patients with cancer. So understand the mechanisms responsible for this process are one of the top goals of cancer research. The metastatic process involves a series of steps chained where the primary tumor invades surrounding tissue and ends spreading throughout the body. One of the first tissues […]
IDIBELL launches ‘Caenorhabditis elegans’ Facility
C. elegans is a nematode that measures millimetre of length, approximately. It has been used to study the genetics of development and the nervous system, and in recent years is making contributions to the study of aging, cell death and genome structure. In 1998 it has been published the complete sequence of its genome, comprising […]
Luis Serrano: “Modify the concentration of a protein, an epigenetic change, may result in disease”
The director of the Center for Genomic Regulation (CRG) in Barcelona, Luis Serrano, explained the latest developments of his research group on Systems Biology in a conference of the series of seminars IDIBELL on February 24. One of the highlights of the Serrano team is to study proteins, not as single molecules, but as parts […]
Pablo Meyer: ”The distribution of enzymes in the cell is like a mirror of its metabolic status”
The researcher of the Thomas J. Watson Research Center, IBM Research in New York, Pablo Meyer, explained in a special seminar on 16 February his research on the regulation of cellular metabolism based on the distribution of enzymes and mitochondria in the cytoplasm. Meyer and his team have shown in E.coli that the location and […]