2023

The natural antioxidant L-Ergothioneine prevents the formation of cystine stones in a murine model of cystinuria

Treatment with L-Ergothioneine manages to increase the solubility of cystine in urine, thus preventing the formation of stones or delaying their appearance. After treatment, an improvement in the oxidative status and mitochondrial function in the kidney is also observed. If these results are validated in future clinical trials, a new preventive treatment for this disease would be available.

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Researchers outline the mechanisms that control the conversion between fetal and adult intestinal stem cells

In the two published studies, the scientific team uses the intestine organoid as a model, a three-dimensional structure similar to mini-intestines created in the laboratory from stem cells. Deciphering the functioning of some transcription factors in the formation of the intestine has been the objective of the team.

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New collaboration agreement with the ICR and Vivan Therapeutics to design new personalized treatments against cancer

A collaboration has been signed between the Bellvitge Biomedical Research Institute (IDIBELL), the Institute of Cancer Research (ICR) in London, and Vivan Therapeutics to jointly develop molecules that recognize more than one target for personalized treatment of colorectal cancer.

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Barcelona becomes the European scientific capital of ALS thanks to the ENCALS International Congress

The local person in charge of the congress is Dra. Mònica Povedano, coordinator of the Motor Neuron Disease Functional Unit of the Bellvitge University Hospital (HUB) and principal researcher of the research group on Neurological and Neurogenetic Diseases of IDIBELL.

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Monotherapy could replace combination therapy in endocarditis

Researchers from the Respiratory Infections and Immunocompromised Host group at IDIBELL and the Bellvitge University Hospital have shown that monotherapy with a 3rd generation cephalosporin is effective and safe as a treatment for this serious infectious disease. These results will change international recommendations for its management.

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A heart stem cell-based model reveals why the same mutation affects two siblings with heart disease differently

Thanks to the model, the IDIBELL team detected that one of the siblings had an additional genetic variant responsible for the greater severity of the pathology. These models offer the possibility of exploring each patient’s pathology and designing an individualized approach.

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