TGF-beta and cancer


The group consists of four principal investigators, whose lines of research have as a common link to advance in the knowledge of the molecular mechanisms that influence tumor cell plasticity and the tumor-stroma interactions. The group has a special interest on the role of transforming growth factor (TGF)-β in regulating these processes, as well as on deciphering the relevance of other signaling pathways, such as epidermal growth factor (EGF) or interferon (IFN) signaling. The research is mainly focused on liver, pancreatic and skin cancer, but additional models are also being worked in collaboration with other groups.




Fabregat Romero, Maria Isabel

Principal investigators


Group leaders
  • Fabregat Romero, María Isabel
Principal investigators
Clinical researchers
Postdoctoral researchers
Investigadors/es predoctorals
Scientific support
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