TGF-beta and cancer


The group consists of two principal investigators (Àngels Fabra and Isabel Fabregat) who lead independent laboratories, but who came together a few years ago to work in close collaboration and become more competitive. The common link between the two is their interest in the transforming growth factor (TGF)-β, a cytokine with pleiotropic actions, the signalling of which is involved in human physiology and pathology. The group’s main aim is to establish whether the TGF-β pathway is a therapeutic target in liver fibrosis and cancer (IF Lab) and in cutaneous and uveal melanoma (AF Lab).



Fabregat Romero, Maria Isabel

Fabregat Romero, Maria Isabel

Principal investigators

Fabregat Romero, Maria Isabel

Fabregat Romero, Maria Isabel


Fabra Fres, Angels


Vaquero Rodriguez, Javier


Group leaders
  • Fabregat Romero, María Isabel
Principal investigators
Clinical researchers
Postdoctoral researchers (R2)
Investigadors/es predoctorals (R1)
Scientific support
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