Epidemiology of bacterial infections. Research on pathogenesis and molecular basis of antimicrobial resistance

Summary

This group’s research covers various lines of clinical and microbiological research, and includes multiple-antibiotic-resistant bacterial infectious, which are a large cause of morbidity and mortality. The study of risk factors and clinical characteristics in hospital-acquired infections, as well as the knowledge of genotypes, virulence factors and mechanisms of antibiotic resistance of bacterial pathogens, are essential for controlling epidemic outbreaks due to multi-resistant bacteria.

758 Publications

Strategic lines

Clinical and molecular epidemiology of pneumococcal disease
Clinical and molecular epidemiology of bacteraemia/sepsis
Clinical and molecular epidemiology of methicillin-resistant S. aureus infections.
Dynamic of microbial populations in exacerbations of chronic obstructive pulmonary disease.
Molecular characterisation of invasive strains of S. pyogenes.
Antimicrobial resistance: phenotype characterisation and study of molecular bases.
New techniques in microbiological diagnosis.
Application of atomic force microscopy in the study of oral biofilm.

Selected Publications

Risk Factors for Treatment Failure and Mortality Among Hospitalized Patients With Complicated Urinary Tract Infection: A Multicenter Retrospective Cohort Study (RESCUING Study Group).

Eliakim-Raz N, Babitch T, Shaw E, Addy I, Wiegand I, Vank C, Torre-Vallejo L, Joan-Miquel V, Steve M, Grier S, Stoddart M, Nienke C, Leo VDH, Vuong C, MacGowan A, Carratalà J, Leibovici L, Pujol M, RESCUING Study

CLINICAL INFECTIOUS DISEASES (ISSN: 1058-4838) 2019

Grillo S, Cuervo G, Carratalà J, Grau I, Pallarès N, Tebé C, Guillem Tió L, Murillo O, Ardanuy C, Domínguez MA, Shaw E, Gudiol C, Pujol M

CLINICAL INFECTIOUS DISEASES (ISSN: 1058-4838) 2019

Assessment of trimethoprim-sulfamethoxazole susceptibility testing methods for fastidious Haemophilus spp.

Sierra Y, Tubau F, González-Díaz A, Carrera-Salinas A, Moleres J, Bajanca-Lavado P, Garmendia J, Domínguez MÁ, Ardanuy C, Martí S

CLINICAL MICROBIOLOGY AND INFECTION (ISSN: 1198-743X) 2019

Emerging non-13-valent pneumococcal conjugate vaccine (PCV13) serotypes causing adult invasive pneumococcal disease in the late-PCV13 period in Spain

González-Díaz A., Càmara J., Ercibengoa M., Cercenado E., Larrosa N., Quesada M.D., Fontanals D., Cubero M., Marimón J.M., Yuste J., Ardanuy C.

CLINICAL MICROBIOLOGY AND INFECTION (ISSN: 1198-743X) 2019

Emergence of multidrug resistance among Haemophilus parainfluenzae from respiratory and urogenital samples in Barcelona, Spain

Sierra Y., González-Díaz A., Tubau F., Imaz A., Cubero M., Càmara J., Ayats J., Martí S., Ardanuy C.

SCI. REP.. 9(1): 4481-4481

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (ISSN: 0934-9723) 2020

Selected Projects

Impacto de un programa de antibióticos con acceso a expertos en enfermedades infecciosas en atención primaria: Estudio controlado no ciego con aleatorización por conglomerados (PROAP)

Shaw Perujo, Evelyn (Principal investitador (PI))

Funder:

FIS-Instituto de Salud Carlos III

1/1/2020 - 31/12/2022

Impacto del genoma accesorio de Streptococcus pneumoniae en la resistencia y la patogenia de la enfermedad

Ardanuy Tisaire, Carmen (Principal investitador (PI))

Funder:

FIS-Instituto de Salud Carlos III

1/1/2019 - 31/12/2021

Performance evaluation of the immuview s. pneumoniae and l. penumophila urinary antigen test

Ardanuy Tisaire, Carmen (Principal investitador (PI))

Funder reference:

PR403/18

19/2/2019 - 19/2/2024

Epidemiological study to estimate the o-serotype distribution of extraintestinal pathogenic escherichia coli (expec) isolated from hospitalized patients of all age groups with invasive expec disease (IED) and to evaluate the clinical case definition and risk factors

Pujol Rojo, Miguel (Principal investitador (PI))

Ref.: PI16/01382

Funder reference:

63871860BAC0006

21/12/2018 - 21/12/2020

Caracterización de las infecciones urinarias bacteriémicas relacionadas con la asistencia sanitaria y comparación con infecciones urinarias bacteriémicas nosocomiales en la era de la resistencia múltiple a fármacos (Itubras-2)

Grau Garriga, Immaculada (Principal investitador (PI))

Funder reference:

MSD-CEF-2017-01

21/9/2017 - 31/12/2026

Technology transfer

Process for manufacturing a customizable medical device and device obtained by said process

ROSELL GRATACOS ANTONI (Inventores-as/autores-as/obtentores-as); BORROS GÓMEZ SALVADOR (Inventores-as/autores-as/obtentores-as); GILABERT PORRES JOAN (Inventores-as/autores-as/obtentores-as); Marti Marti, Sara (Inventores-as/autores-as/obtentores-as); MARTÍ MARTÍ SARA (Inventores-as/autores-as/obtentores-as); MONTES WORBOYS ANA (Inventores-as/autores-as/obtentores-as); Montes Worboys, Ana (Inventores-as/autores-as/obtentores-as); RAMOS PÉREZ VÍCTOR (Inventores-as/autores-as/obtentores-as); MOLINA MOLINA MARIA (Inventores-as/autores-as/obtentores-as)

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