2011

IDIBELL Researchers discover why tumour cells change their appearance

If environmental conditions of tumors are changed, the process reverses The study is led by Manel Esteller Like snakes, tumour cells shed their skin. Cancer is not a static disease but during its development the disease accumulates changes to evade natural defences adapting to new environmental circumstances, protecting against chemotherapy and radiotherapy and invading neighbouring organs, eventually causing metastasis. Article reference

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Morbid obesity and low weight are genetically related

A study published in the journal Nature has found in a region in chromosome 16 the tendency to suffer from obesity or underweight. The study has the participation of researchers from the Psychiatry and Mental Health research group at IDIBELL and the Networking Biomedical Research Centre on the Physiopathology of Obesity and Nutrition (CIBERobn). Article

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46% of IDIBELL smokers plan to quit smoking

The tobacco consumption survey shows that over 25% of staff is smoker and almost half of them think about quit it someday Under the Smoke-free IDIBELL program, offered by the institute through ICO’s Control Tobacco Unit to all workers who want to quit smoking, it has been performed a poll to assess what is the snuff prevalence among IDIBELL staff and if all workers know about this support program. Quit smoking The poll

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The network of our brain which is active at rest is disabled when performing a task either emotional or cognitive

Published on PLoS ONE IDIBELL researchers have shown that several brain regions known as the Default Mode Network have activity at rest and when we induce a task, this network is disabled. Emotional or cognitive tasks Article’s reference

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An epigenetic change in specific regulatory T cells,protective biomarker for kidney graft outcome

IDIBELL researchers show that methylation of FOXP3 factor controls Regulatory T cell immunosuppressive function A study of the Nephrology and Renal Transplantation research group of the IDIBELL demonstrates that renal transplant patients who present regulatory T cells with high expression of FOXP3 factor demethylated, both in blood or directly into the transplanted organ, have a better functional outcome of the graft. Article’s reference

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An autumn full of scientific events

Meeting of the Spanish Society of Biochemistry and Molecular Biology (SEBBM) International Pharma Licensing Symposium (IPLS). ICC on Genomic Imprinting and Beyond. Medevice Exhibition and Biomaterials Conference. RECOMB 2011. Salón Internacional de la Química. Expoquimia. European Cancer Cluster Partening (ECCP) Interbio Summer School on Structural Biology “NMR applicactions in Protein Reseach”. Biotechnica. BIO-Europe (17th Annual International Partneting Conference). F Medica. Technology Summit & Technology Platform .

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Inhibition of the EGF receptor retrieves the response of liver tumor cells death-inducing factors

The finding may enable progress towards personalized treatments in these kinds of tumors Inhibition of epidermal growth factor receptor (EGFR) impairs the growth of liver tumor cells and makes them sensitive to the suppressive action of the cytokine TGF-beta, by activating mechanisms of programmed death (apoptosis). This is the result of research conducted by researchers from the Biological clues of the invasive and metastatic phenotype group at IDIBELL, led by Isabel Fabregat. Dual role of TGF – beta Article reference

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OTRI wins meters and facilities for researchers

The Research Results Transfer Office (OTRI) and the Research Support Office (ORS) IDIBELL launches new space after the renovations. The renewed OTRI nearly doubles its space from about 70m2 to 135m2 and has more actual daylight. It is structured in three different areas: one for competitive projects, another for non competitive ones and a new meeting room.

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