NeurAntigen: Autoimmune encephalitis diagnose
Problem to be solved
Autoimmune encephalitis (AiE) is a severe auto-inflammatory disorder of the brain affecting patients of all ages. Despite being rare, AiE is included among the top differential diagnoses, being it a key step on its treatment with an urgent need for a sensitive and specific test.
Technology
NeurAntigen kit consists of human iPSC-derived neurons, preserved in optimized conditions to be shipped to diagnostic laboratories. Our kit is able to detect all known AiE-related antibodies (14 different antibodies) using non-neural cells as a control through an immunofluorescent Ab-recognition assay in a fast (2 hours) and user-friendly fashion, using patient’s serum or CSF.
Autors
Antonella Consiglio and Eugenia Martínez (H.Clínic)
Technology Readiness Level
TRL5
What are we looking for?
Partners for license agreement or co-development