Multimorbidity, defined as the coexistence of two or more diseases in a particular individual, represents a major challenge for healthcare quality. It is estimated that approximately 7% of the general population suffers from multimorbidity and this percentage is higher than 50% among the elderly.

However, the trends of associations of diseases depending on age and gender are still not known, and the genetic factors responsible for multimorbidity are unknown too. A better knowledge of these variables and factors would provide better clinical assistance and follow-up, as well as new prevention tools.

In a recent collaborative work, led by researchers from IDIBELL-ICO (ProCURE, Oncobell programs), IDIAP Jordi Gol and GCAT (Genomes of Life, IGTP), the main diseases and associations that contribute significantly to the appearance of multimorbidity are identified. The study also points out inherited genetic factors that have an influence on the appearance of multimorbidity.

Regarding cancer, researchers also identify metabolic processes that are commonly altered in breast cancer, nutritional diseases and neuropathies. These processes also influence the diagnostic age of breast cancer and could therefore become new prevention tools.