Casanovas stresses that these findings may be very clinically relevant, and that therapies that combine inhibition of more than one angiogenic pathway might be useful in circumventing resistance.

In late 2010, the agency Thomson Reuters, in its report Science Watch, stressed a study coordinated by Oriol Casanovas about the negative consequences of antiangiogenic therapies as the most often cited in Biology in 2010. The paper was published in May 2009 in Cancer Cell