La rt-PA \u00e9s un medicament d\u2019administraci\u00f3 intravenosa indicat per als ictus isqu\u00e8mics (emb\u00f2lies, infarts cerebrals), que es produeixen quan alguna de les art\u00e8ries que porten sang al cervell s\u2019obstrueix. El f\u00e0rmac desf\u00e0 el trombe i permet que hi torni a circular la sang. <\/p>\n
Tradicionalment, sempre s\u2019ha contraindicat l\u2019administraci\u00f3 de f\u00e0rmacs trombol\u00edtics a pacients amb un ictus hemorr\u00e0gic. Des de fa uns quants anys, per\u00f2, s\u2019ha vist que en les hemorr\u00e0gies cerebrals intraventriculars l\u2019administraci\u00f3 d\u2019aquest tractament mitjan\u00e7ant un cat\u00e8ter al ventricle cerebral afectat pot ser benefici\u00f3s per desfer els co\u00e0guls que es formen despr\u00e9s del vessament. La t\u00e8cnica redueix les complicacions i millora el pron\u00f2stic dels pacients.<\/p>\n
Estudi cl\u00ednic<\/span><\/p>\n En l\u2019actualitat hi ha diversos hospitals de tot el m\u00f3n que, des de fa anys, han comen\u00e7at a realitzar aquesta t\u00e8cnica amb resultats satisfactoris. L\u2019Hospital de Bellvitge, per exemple, ha tractat 20 pacients des de l\u2019any 2002 amb aquesta t\u00e8cnica. <\/p>\n Malgrat tot, es feia necess\u00e0ria la realitzaci\u00f3 d\u2019un estudi amb un nombre considerable de pacients per tal de poder certificar l\u2019efic\u00e0cia de la rt-PA com a tractament est\u00e0ndard de l\u2019hemorr\u00e0gia intraventricular. Precisament aquest \u00e9s l\u2019objectiu del projecte CLEAR III: dur a terme un assaig cl\u00ednic multic\u00e8ntric per validar la t\u00e8cnica amb 500 pacients d\u2019hospitals de tot el m\u00f3n. <\/p>\n El projecte est\u00e0 finan\u00e7at pel National Health Service dels Estats Units i promogut per la universitat nord-americana Johns Hopkins. El coordinador internacional \u00e9s Daniel Hanley, professor de Neurologia d\u2019aquesta universitat i qui ha desenvolupat la t\u00e8cnica.<\/p>\n A Espanya, el projecte est\u00e0 coordinat pel neurocirurgi\u00e0 de l\u2019Hospital Universitari de Bellvitge i investigador de l\u2019IDIBELL, Alberto Torres D\u00edaz.<\/p>\n Els dies 14 i 15 de gener, es van reunir al Campus de Bellvitge de l\u2019Hospitalet de Llobregat quaranta especialistes que participen en el projecte, procedents de centres d\u2019Israel, Gran Bretanya, Estats Units i Espanya (Hospital Cl\u00ednic, Sant Pau i Bellvitge). La reuni\u00f3 ha servit per definir els protocols que s\u2019han de dur a terme per realitzar l\u2019assaig cl\u00ednic.<\/p>\n Primera causa d\u2019incapacitat<\/span><\/p>\n L\u2019ictus \u00e9s un problema assistencial complex i creixent. Actualment, \u00e9s la primera causa de mort a Catalunya en les dones per sobre dels 65 anys i en els homes per sobre dels 75, i \u00e9s la primera causa d\u2019incapacitat a llarg termini.<\/p>\n El 15% dels ictus s\u00f3n hemorr\u00e0gics. Les causes m\u00e9s freq\u00fcents s\u00f3n la hipertensi\u00f3 arterial i els aneurismes cerebrals cong\u00e8nits (lesi\u00f3 de la paret de l\u2019art\u00e8ria). <\/p>\n Comparat amb l\u2019ictus isqu\u00e8mic, l\u2019hemorr\u00e0gic afecta pacients m\u00e9s joves. Tot i que inicialment es produeixen menys danys al teixit cerebral, a mesura que passen les hores, la sang vessada es coagula i pot produir danys irreversibles.<\/p>\n La mortalitat d\u2019aquest tipus d\u2019ictus hemorr\u00e0gic (hemorr\u00e0gia cerebral intraventricular massiva) arriba fins al 80% dels afectats i la majoria dels supervivents acaben tenint discapacitats motores i cognitives significatives. La combinaci\u00f3 de cirurgia no invasiva amb l\u2019administraci\u00f3 via cat\u00e8ter d\u2019un f\u00e0rmac trombol\u00edtic com la rt-PA suposa una esperan\u00e7a per millorar la superviv\u00e8ncia i la qualitat de vida de les persones afectades.<\/p>\n","protected":false},"excerpt":{"rendered":" La rt-PA \u00e9s un medicament d\u2019administraci\u00f3 intravenosa indicat per als ictus isqu\u00e8mics (emb\u00f2lies, infarts cerebrals), que es produeixen quan alguna de les art\u00e8ries que porten sang al cervell s\u2019obstrueix. El f\u00e0rmac desf\u00e0 el trombe i permet que hi torni a circular la sang. Tradicionalment, sempre s\u2019ha contraindicat l\u2019administraci\u00f3 de f\u00e0rmacs trombol\u00edtics a pacients amb un […]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-09 19:44:00","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9744"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=9744"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9744\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=9744"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=9744"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=9744"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}