Araque ha demostrat que els astr\u00f2cits del hipocamp, la regi\u00f3 cerebral implicada en processos de mem\u00f2ria i aprenentatge, poden alliberar un neurotransmissor: el glutamat, que potencia la transmissi\u00f3 nerviosa de les neurones. Participant aix\u00ed en una sinapsi tripartida \u201cl\u2019astr\u00f2cit no regula la conversa entre neurones, participa activament en ella. \u00c9s una conversa a tres bandes\u201d explica l’investigador. <\/p>\n
Segons Araque, aprofundir en el coneixement de la funci\u00f3 de la xarxa neuroglial \u00e9s nom\u00e9s \u201cun primer pas per a entendre les malalties neurodegeneratives com l\u2019Alzheimer o el Parkinson. Descobrir si els astr\u00f2cits estan implicats en aquestes patologies i investigar si poden ser \u00fatils a l’hora d’implantar noves ter\u00e0pies\u201d. <\/p>\n
El Dr. Alfonso Araque va obtenir el seu doctorat sota la supervisi\u00f3 del neurofisi\u00f2leg espanyol Dr. Washington Bu\u00f1o a<\/p>\n
l’Institut Cajal de Madrid. El seu treball es va orientar fonamentalment a la comprensi\u00f3 de l’equilibri entre les sinapsis excitadores i inhibidores que regulen l’activitat motora del cranc de riu. En els noranta es va traslladar al laboratori del Dr. Philip Haydon a<\/p>\n
Iowa, on va comen\u00e7ar a treballar en la interacci\u00f3 dels astr\u00f2cits i les sinapsis. Des d’aquest laboratori s’ha llan\u00e7at la hip\u00f2tesi de la sinapsis tripartida, en la qual els astr\u00f2cits podrien participar en el proc\u00e9s de codificaci\u00f3 de la transmissi\u00f3 sin\u00e0ptica. Araque va arribar a l’Institut Ram\u00f3n i Cajal, on va contribuir a aquesta hip\u00f2tesi obtenint evid\u00e8ncies experimentals molt s\u00f2lides.<\/p>\n","protected":false},"excerpt":{"rendered":"
Araque ha demostrat que els astr\u00f2cits del hipocamp, la regi\u00f3 cerebral implicada en processos de mem\u00f2ria i aprenentatge, poden alliberar un neurotransmissor: el glutamat, que potencia la transmissi\u00f3 nerviosa de les neurones. Participant aix\u00ed en una sinapsi tripartida \u201cl\u2019astr\u00f2cit no regula la conversa entre neurones, participa activament en ella. \u00c9s una conversa a tres bandes\u201d […]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-9699","post","type-post","status-publish","format-standard","hentry","category-sin-categorizar"],"publishpress_future_action":{"enabled":false,"date":"2024-11-25 03:22:52","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9699","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=9699"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9699\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=9699"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=9699"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=9699"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}