{"id":9695,"date":"2011-01-24T00:00:00","date_gmt":"2011-01-23T23:00:00","guid":{"rendered":"https:\/\/idibell.cat\/blog\/2011\/01\/24\/lepigenetica-es-el-seguent-pas-en-la-comprensio-de-la-diferenciacio-cel%c2%b7lular\/"},"modified":"2020-05-13T19:50:56","modified_gmt":"2020-05-13T17:50:56","slug":"lepigenetica-es-el-seguent-pas-en-la-comprensio-de-la-diferenciacio-cel%c2%b7lular","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2011\/01\/lepigenetica-es-el-seguent-pas-en-la-comprensio-de-la-diferenciacio-cel%c2%b7lular\/","title":{"rendered":"L\u2019epigen\u00e8tica \u00e9s el seg\u00fcent pas en la comprensi\u00f3 de la diferenciaci\u00f3 cel\u00b7lular&#8217;"},"content":{"rendered":"<p><span style=\"color: #58585a; font-family: Arial; font-size: 12px; text-align: justify;\">Les c\u00e8l\u00b7lules mare adultes indu\u00efdes poden diferenciar-se en qualsevol tipus de c\u00e8l\u00b7lula per\u00f2 ho fan de manera m\u00e9s r\u00e0pida si es diferencien en el tipus de c\u00e8l\u00b7lula al qual pertanyien abans de la reprogramaci\u00f3. Aix\u00f2 \u00e9s a causa de la seva mem\u00f2ria epigen\u00e8tica. Amb aquest argument el director cient\u00edfic de la Fundaci\u00f3 IVI i de l&#8217;Institut Pr\u00edncep Felipe de Val\u00e8ncia, el doctor Carlos Sim\u00f3n, ha confirmat la necessitat d&#8217;aplicar la epigen\u00e8tica al camp de la investigaci\u00f3 de les c\u00e8l\u00b7lules mare en el qual duu treballant l&#8217;\u00faltima d\u00e8cada. Ho ha fet en el marc del cicle de seminaris del IDIBELL el passat 21 de gener.<\/span> <\/p>\n<p> Sim\u00f3n ha explicat les particularitats dels tipus de c\u00e8l\u00b7lula mare utilitzats en la investigaci\u00f3 del proc\u00e9s de diferenciaci\u00f3 cel\u00b7lular: c\u00e8l\u00b7lules mare embrion\u00e0ries, c\u00e8l\u00b7lules mare adultes i c\u00e8l\u00b7lules mare indu\u00efdes. Ha destacat que, en medicina reproductiva, \u201ces coneix el proc\u00e9s des del seu vessant gen\u00e8tic i, en aquest sentit, som capa\u00e7os de diferenciar una c\u00e8l\u00b7lula embrion\u00e0ria en un espermatozoide. No obstant aix\u00f2, som incapa\u00e7os d&#8217;aconseguir que l&#8217;embri\u00f3 del ratol\u00ed resultant surti endavant. Per aix\u00f2 \u00e9s important aprofundir en com la epigen\u00e9tica participa en la diferenciaci\u00f3 cel\u00b7lular.\u201d <\/p>\n<p> Des de fa alguns anys, el doctor Carlos Sim\u00f3n, treballa amb les c\u00e8l\u00b7lules del endometri: \u201cdos ter\u00e7os d&#8217;aquest teixit es destrueixen cada mes i es regeneren. S\u00f3n c\u00e8l\u00b7lules mare adultes amb moltes possibilitats en la investigaci\u00f3. Poden ajudar-nos a comprendre i a prevenir la endometriosis, una malaltia que afecta al 20% de les dones\u201d. <\/p>\n<p> <strong>Sobre Carlos Sim\u00f3n<\/strong> <\/p>\n<p> El Dr. Carlos Sim\u00f3n \u00e9s professor titular de Obstetricia i Ginecolog\u00eda en la Universitat de Val\u00e8ncia, Director cient\u00edfic de la Fundaci\u00f3 IVI i de l&#8217;Institut Pr\u00edncep Felipe de Val\u00e8ncia (CPIF). El seu treball se centra en la implantaci\u00f3 embrion\u00e0ria, receptivitat uterina, c\u00e8l\u00b7lules mare, embrion\u00e0ries i adultes. Durant la d\u00e8cada dels noranta la seva investigaci\u00f3 va contribuir a l&#8217;avan\u00e7 de la medicina reproductiva, espec\u00edficament en la comprensi\u00f3 de la receptivitat de l\u2019endometri hum\u00e0, la viabilitat de l&#8217;embri\u00f3, la implantaci\u00f3 embrion\u00e0ria i la endometriosis. I des del 2001, Sim\u00f3n ha ampliat la seva investigaci\u00f3 al camp de les c\u00e8l\u00b7lules mare embrion\u00e0ries humanes amb assoliments com la derivaci\u00f3 de les dues primeres c\u00e8l\u00b7lules mare a Espanya o l&#8217;obtenci\u00f3 de c\u00e8l\u00b7lules mare sense destruir l&#8217;embri\u00f3 hum\u00e0. En les seves \u00faltimes investigacions ha assolit la identificaci\u00f3 i caracteritzaci\u00f3 de les c\u00e8l\u00b7lules mare del endometri.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sobre Carlos Sim\u00f3n<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-12 08:35:27","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9695"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=9695"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9695\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=9695"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=9695"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=9695"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}