Coltheres utilitzar\u00e0 els c\u00e0ncers colorectals com a banc de proves per a definir biomarcadors espec\u00edfics \u00fatils per al disseny de tractaments personalitzats. El consorci est\u00e0 obert a la possibilitat que la ind\u00fastria farmac\u00e8utica pugui determinar quins pacients tenen m\u00e9s probabilitats de respondre als seus nous tractaments contra el c\u00e0ncer i realitzar assaigs cl\u00ednics r\u00e0pids de test de concepte <\/p>\n
El consorci est\u00e0 integrat per unitats cl\u00edniques pioneres en test de biomarcadors en ter\u00e0pies personalitzades i grups de recerca translacional l\u00edders amb una traject\u00f2ria provada a l\u2019hora de desenvolupar diagn\u00f2stics per a ter\u00e0pies contra el c\u00e0ncer. \u00c9s important destacar que el consorci europeu inclou dues empreses: Horizon Discovery (Regne Unit) i Agendia (Holanda). La primera desenvolupar\u00e0 nous models cel\u00b7lulars de c\u00e0ncer amb<\/p>\n
nous biomarcadors predictius de la resposta farmacol\u00f2gica, determinats pels perfils dels pacients que proporcionin els membres del consorci. Per la seva banda, Agendia desenvolupar\u00e0 proves per predir la resposta del pacient a les ter\u00e0pies bassades en la signatura gen\u00f2mica de cada tumor. <\/p>\n
El director del Programa d\u2019Epigen\u00e8tica i Biologia Cel\u00b7lular del C\u00e0ncer de l\u2019IDIBELL, que participa en el consorci, Manel Esteller, ha explicat que \u201cColtheres ha estat dissenyat per incorporar el tractament personalitzat del c\u00e0ncer en la pr\u00e0ctica cl\u00ednica utilitzant els tumors colorectals com a model\u201d. Esteller ha mostrat la seva satisfacci\u00f3 per formar part d\u2019aquest projecte de la UE que compta amb experts internacionals en els camps de la gen\u00e8tica funcional, l\u2019epigen\u00f2mica, la farmacogen\u00e8tica i l\u2019oncologia cl\u00ednica. Ha explicat que l\u2019aportaci\u00f3 de l\u2019IDIBELL a Coltheres \u201cser\u00e0 obtenir perfils epigen\u00f2mics dels pacients i dels models experimentals per trobar nous biomarcadors de pron\u00f2stic i de resist\u00e8ncia a f\u00e0rmacs en c\u00e0ncer colorectal\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"
En el consorci Coltheres participen hospitals i centres de recerca translacional de sis pa\u00efsos europeus<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-14 04:18:07","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9665"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=9665"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9665\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=9665"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=9665"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=9665"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}