{"id":9641,"date":"2011-06-14T00:00:00","date_gmt":"2011-06-13T22:00:00","guid":{"rendered":"https:\/\/idibell.cat\/blog\/2011\/06\/14\/manuel-ramirez-un-cop-hem-aconseguit-fer-el-pas-del-laboratori-al-pacient-hem-de-tornar-al-laboratori-per-continuar-avancant\/"},"modified":"2020-05-13T19:50:40","modified_gmt":"2020-05-13T17:50:40","slug":"manuel-ramirez-un-cop-hem-aconseguit-fer-el-pas-del-laboratori-al-pacient-hem-de-tornar-al-laboratori-per-continuar-avancant","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2011\/06\/manuel-ramirez-un-cop-hem-aconseguit-fer-el-pas-del-laboratori-al-pacient-hem-de-tornar-al-laboratori-per-continuar-avancant\/","title":{"rendered":"Manuel Ram\u00edrez: \u201cUn cop hem aconseguit fer el pas del laboratori al pacient, hem de tornar al laboratori per continuar avan\u00e7ant\u201d"},"content":{"rendered":"<p><strong>El<\/p>\n<p> pediatra i onc\u00f2leg Manuel Ram\u00edrez ha explicat en una confer\u00e8ncia a  l\u2019IDIBELL el passat 10 de juny la seva experi\u00e8ncia cl\u00ednica en nens amb  tumors s\u00f2lids tractats amb el virus ICOVIR 5, dissenyat pel grup de  viroter\u00e0pia de l\u2019IDIBELL liderat per Ramon Alemany, a la Unitat  d&#8217;Hematologia Pedi\u00e0trica i Oncol\u00f2gica de l&#8217;Hospital Nen Jes\u00fas de Madrid  on encap\u00e7ala un grup de recerca per al desenvolupament de noves ter\u00e0pies  per a nens amb c\u00e0ncer. <br \/><\/strong> <strong><br \/><\/strong> L\u2019ICOVIR 5 \u00e9s un adenovirus amb capacitat d\u2019oncolisis (infecta i descompon les c\u00e8l\u00b7lules tumorals). \u201cNosaltres no apliquem el virus directament de forma local perqu\u00e8 tractem tumors metast\u00e0tics\u201d ha explicat Ram\u00edrez, \u201cel que fem \u00e9s utilitzar c\u00e8l\u00b7lules mesenquimals de medul\u00b7la \u00f2ssia del mateix pacient, les cultivem i les infectem amb el virus perqu\u00e8 facin de vehicle fins a la zona tumoral\u201d. El tractament no ha produ\u00eft en cap cas efectes secundaris m\u00e9s enll\u00e0 de febre. Pel que fa els resultats de la viroter\u00e0pia han estat diversos: \u201cNom\u00e9s en un cas hem vist una remissi\u00f3 completa del tumor, mentre que un dels pacients s\u2019ha estabilitzat i en altres tres el tumor ha progressat\u201d. <\/p>\n<p> La seg\u00fcent pregunta que es fa Manuel Ram\u00edrez \u00e9s si en alguns casos, com el de la remissi\u00f3 del tumor a m\u00e9s de l\u2019oncolisi s\u2019ha produ\u00eft tamb\u00e9 una resposta immune antitumoral. I aquesta pregunta \u00e9s la que el fa tornar la laboratori: \u201cHem fet el pas de la recerca traslacional del laboratori al pacient, per\u00f2 per continuar avan\u00e7ant hem de tornar al laboratori. En els pacients no podem fer proves per ajustar dosi o per comprovar si realment hi ha aquesta resposta immune antitumoral o si la podem provocar\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>El\u00a0 pediatra i onc\u00f2leg Manuel Ram\u00edrez ha explicat en una confer\u00e8ncia a  l\u2019IDIBELL el passat 10 de juny la seva experi\u00e8ncia cl\u00ednica en nens amb  tumors s\u00f2lids tractats amb el virus ICOVIR 5, dissenyat pel grup de  viroter\u00e0pia de l\u2019IDIBELL liderat per Ramon Alemany, a la Unitat  d&#8217;Hematologia Pedi\u00e0trica i Oncol\u00f2gica de l&#8217;Hospital Nen Jes\u00fas de Madrid  on encap\u00e7ala un grup de recerca per al desenvolupament de noves ter\u00e0pies  per a nens amb c\u00e0ncer.<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-09 21:14:02","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9641"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=9641"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9641\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=9641"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=9641"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=9641"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}