{"id":9619,"date":"2011-09-09T00:00:00","date_gmt":"2011-09-08T22:00:00","guid":{"rendered":"https:\/\/idibell.cat\/blog\/2011\/09\/09\/lus-del-diu-redueix-a-la-meitat-el-risc-de-cancer-de-coll-duter\/"},"modified":"2020-05-13T19:50:30","modified_gmt":"2020-05-13T17:50:30","slug":"lus-del-diu-redueix-a-la-meitat-el-risc-de-cancer-de-coll-duter","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2011\/09\/lus-del-diu-redueix-a-la-meitat-el-risc-de-cancer-de-coll-duter\/","title":{"rendered":"L\u2019\u00fas del DIU redueix a la meitat el risc de c\u00e0ncer de coll d\u2019\u00fater"},"content":{"rendered":"<p><strong>Els dispositius intrauterins (DIU) podrien protegir contra el c\u00e0ncer  cervical o de coll d\u2019\u00fater. Els resultats de l\u2019estudi epidemiol\u00f2gic m\u00e9s  ampli fet fins a la data en el qual ha participat el grup de recerca en  Virus i C\u00e0ncer de l&#8217;IDIBELL es publiquen a l&#8217;edici\u00f3 electr\u00f2nica de <a href=\"http:\/\/www.thelancet.com\/home\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"enllac\">The Lancet Oncology<\/span><\/a>.<\/strong> <\/p>\n<p> Els resultats mostren que les dones que havien utilitzat un DIU redu\u00efen a la meitat el risc de desenvolupar c\u00e0ncer cervical en comparaci\u00f3 amb les que no l\u2019havien fet servir mai. Aquests resultats s\u00f3n contraris a la creen\u00e7a popular que el DIU podria ser un factor de risc de c\u00e0ncer cervical. Els estudis anteriors sobre els possibles efectes del seu \u00fas en el desenvolupament d\u2019aquest c\u00e0ncer no havien mostrar resultats concloents. <\/p>\n<p> Xavier Castellsagu\u00e9, investigador del grup de Virus i C\u00e0ncer de l\u2019IDIBELL i del programa d\u2019Investigaci\u00f3 en Epidemiologia del C\u00e0ncer de l\u2019<a href=\"http:\/\/www.iconcologia.net\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"enllac\">Institut Catal\u00e0 d\u2019Oncologia<\/span><\/a> (ICO) el seu equip van avaluar els efectes de l\u2019\u00fas del DIU en el risc de c\u00e0ncer cervicouter\u00ed papil\u00b7loma hum\u00e0 (VPH) i el risc de desenvolupar c\u00e0ncer de coll uter\u00ed o cervical. Per fer-ho van analitzar les dades de deu estudis de casos control de c\u00e0ncer cervical realitzats en vuit pa\u00efsos, i setze estudis de prevalen\u00e7a del VPH en dones de quatre continents. <\/p>\n<p> Els resultats es van ajustar tenint en compte factors de confusi\u00f3 com el nombre de citologies, el nombre de parelles sexuals o l\u2019edat de la primera relaci\u00f3 sexual entre d\u2019altres. <\/p>\n<p> <strong>Reducci\u00f3 del risc a la meitat<\/strong> <\/p>\n<p> L\u2019\u00fas del DIU no va afectar el risc d\u2019infecci\u00f3 per VPH per\u00f2 es va associar amb un risc significativament menor de c\u00e0ncer de coll uter\u00ed pels dos<\/p>\n<p> tipus majoritaris de c\u00e0ncer cervical, reduint la probabilitat de desenvolupar carcinoma de c\u00e8l\u00b7lules escamoses en un 44% i l\u2019adenocarcinoma o carcinoma adenoescam\u00f3s en un 54%. <\/p>\n<p> Curiosament, el temps d\u2019\u00fas del DIU no va alterar significativament el risc de c\u00e0ncer cervical. El risc es va reduir gaireb\u00e9 a la meitat en el primer any d\u2019\u00fas i l\u2019efecte protector va continuar sent significatiu despr\u00e9s de deu anys d\u2019\u00fas. <\/p>\n<p> Els autors de l\u2019estudi afirmen que \u201cles associacions trobades a l\u2019estudi suggereixen que l\u2019\u00fas del DIU no modifica la probabilitat de contreure una infecci\u00f3 per VHP (la causa del c\u00e0ncer cervical), per\u00f2 podria afectar a la probabilitat de progressi\u00f3 del VPH a c\u00e0ncer cervical\u201d. <\/p>\n<p> Entre les possibles explicacions per aquest efecte protector dels DIU, els autors assenyalen o b\u00e9 que el proc\u00e9s d\u2019inserci\u00f3 o de retirada del dispositiu destrueix les lesions precanceroses, o b\u00e9 que el dispositiu indueix una inflamaci\u00f3 cr\u00f2nica de la mucosa i una resposta immune de llarga duraci\u00f3, reduint aix\u00ed la probabilitat de progressi\u00f3 del VPH. <\/p>\n<p> <strong>Refer\u00e8ncia de l\u2019article<\/strong> <strong><\/p>\n<p><\/strong> Castellsag\u00fae X.*, D\u00edaz M.*, Vaccarella S., de Sanjos\u00e9 S.*, Mu\u00f1oz N., Herrero R., Franceschi S., Meijer C. and Bosch X*.Intrauterine device use, cervical human papillomavirus, and risk of cervical cancer: a pooled analysis of 26 epidemiological studies. The Lancet Oncolgy 2011. DOI:10.1016\/S1470-2045(11)70223-6. <\/p>\n<p> *Investigadors de l\u2019IDIBELL<\/p>\n","protected":false},"excerpt":{"rendered":"<p>L\u2019estudi s\u2019ha realitzat amb m\u00e9s de 20 mil dones de diversos pa\u00efsos Els dispositius intrauterins (DIU) podrien protegir contra el c\u00e0ncer  cervical o de coll d\u2019\u00fater. Els resultats de l\u2019estudi epidemiol\u00f2gic m\u00e9s  ampli fet fins a la data en el qual ha participat el grup de recerca en  Virus i C\u00e0ncer de l&#8217;IDIBELL es publiquen a l&#8217;edici\u00f3 electr\u00f2nica de The Lancet Oncology. Reducci\u00f3 del risc a la meitat Refer\u00e8ncia de l\u2019article<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-9619","post","type-post","status-publish","format-standard","hentry","category-sin-categorizar"],"publishpress_future_action":{"enabled":false,"date":"2025-01-01 10:32:34","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9619","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=9619"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9619\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=9619"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=9619"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=9619"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}