{"id":9616,"date":"2011-09-19T00:00:00","date_gmt":"2011-09-18T22:00:00","guid":{"rendered":"https:\/\/idibell.cat\/blog\/2011\/09\/19\/andrew-plested-volem-saber-com-les-neurones-obtenen-informacio-com-lemmagatzemen-i-com-la-processen\/"},"modified":"2020-05-13T19:50:27","modified_gmt":"2020-05-13T17:50:27","slug":"andrew-plested-volem-saber-com-les-neurones-obtenen-informacio-com-lemmagatzemen-i-com-la-processen","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2011\/09\/andrew-plested-volem-saber-com-les-neurones-obtenen-informacio-com-lemmagatzemen-i-com-la-processen\/","title":{"rendered":"Andrew Plested:  \u201cVolem saber com les neurones obtenen informaci\u00f3, com l\u2019emmagatzemen i com la processen\u201d"},"content":{"rendered":"<p><strong>Per respondre aquestes ambicioses preguntes, el treball d&#8217;Andrew  Plested, se centra en una de les peces que intervenen en aquests  processos: els receptors de glutamat. \u201cSi entenem com funcionen,  entendrem les connexions neuronals i com el cervell processa i  emmagatzema informaci\u00f3\u201d. Plested va explicar els seus aven\u00e7os en el  seminari IDIBELL del16 de setembre.<\/strong> <\/p>\n<p> L\u2019objectiu del  laboratori de Neuroci\u00e8ncia Molecular i Biof\u00edsica de l\u2019Institut Leibniz  de Farmacologia Molecular de Berlin, liderat per l\u2019investigador Andrew  Plested, \u00e9s con\u00e8ixer a fons l\u2019estructura, i els mecanismes dels  receptors de glutamat per entendre com funciona la transmissi\u00f3 sin\u00e0ptica  al nostre cervell. <\/p>\n<p> Els receptors del  glutamat intervenen en el 60% de les sinapsis al nostre cervell. \u201cEn el  futur, el seu estudi podria ser un primer pas en la recerca de noves  ter\u00e0pies de malalties cerebrals\u201d, diu l\u2019investigador, \u201cper  exemple, un augment important del glutamat al cervell, provoca la  sobreactivaci\u00f3 dels receptors i finalment, la mort de les c\u00e8l\u00b7lules i un  vessament cerebral. Si coneixem millor aquest mecanisme podr\u00edem  investigar nous tractaments\u201d. Plested per\u00f2, ha afegit que \u201cel  coneixement d\u2019aquests mol\u00e8cules no serveix nom\u00e9s per estudiar malalties  sin\u00f3 tamb\u00e9 per comprendre com funciona el nostre cervell\u201d. <\/p>\n<p> En aquest sentit el  grup d\u2019Andrew Plested estudia el proc\u00e9s de dessensibilitzaci\u00f3: <\/p>\n<p>Es  desconeix per qu\u00e8, en alguns casos, tot i que el glutamat est\u00e0 unit al  seu receptor no es produeix la resposta sin\u00e0ptica. L\u2019investigador est\u00e0  conven\u00e7ut que \u201cl\u2019estudi d\u2019aquest proc\u00e9s podria respondre preguntes sobre  els processos de desenvolupament cerebral o d\u2019aprenentatge. Hi ha  senyal per\u00f2 no hi ha resposta. Quin sentit t\u00e9? Durant anys s\u2019ha cregut  que no tenia import\u00e0ncia per\u00f2 ara s\u2019ha vist que \u00e9s cr\u00edtic pel  desenvolupament cerebral\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Per respondre aquestes ambicioses preguntes, el treball d&#8217;Andrew  Plested, se centra en una de les peces que intervenen en aquests  processos: els receptors de glutamat. \u201cSi entenem com funcionen,  entendrem les connexions neuronals i com el cervell processa i  emmagatzema informaci\u00f3\u201d. Plested va explicar els seus aven\u00e7os en el  seminari IDIBELL del16 de setembre.<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-9616","post","type-post","status-publish","format-standard","hentry","category-sin-categorizar"],"publishpress_future_action":{"enabled":false,"date":"2024-12-01 01:51:46","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9616","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=9616"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9616\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=9616"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=9616"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=9616"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}