El gastroenter\u00f2leg de l\u2019Hospital Universitari de Rangueil, a Touluse, i investigador de l\u2019INSERM, Louis Buscail ha explicat els seus darrers aven\u00e7os en ter\u00e0pia g\u00e8nica contra el c\u00e0ncer de p\u00e0ncrees avan\u00e7at al cicle de seminaris IDIBELL el passat 11 de novembre. <\/p>\n
Actualment, l\u2019\u00fanic tractament eficient contra el c\u00e0ncer de p\u00e0ncrees \u00e9s la cirurgia. L\u2019agent quimioter\u00e0peutic gemcitabina millora l\u2019estat del pacient per\u00f2 la seva superviv\u00e8ncia no s\u2019allarga. L\u2019equip de Louis Buscail ha dissenyat una nova ter\u00e0pia g\u00e8nica mitjan\u00e7ant \u201cun compost gen\u00e8tic que sensibilitza les c\u00e8l\u00b7lules tumorals a la gemcitabina fent que aquesta resulti molt m\u00e9s eficient ja qu\u00e8 indueix la mort cel\u00b7lular per apoptosi i la regressi\u00f3 tumoral\u201d. <\/p>\n
Despr\u00e9s de provar aquesta ter\u00e0pia en animals, l\u2019any 2010 Buscail va posar en marxa un assaig cl\u00ednic fase I amb 12 pacients. A l\u2019espera dels resultats, l\u2019investigador franc\u00e8s es mostra prudent i assegura que \u201ccal anar pas a pas. El nostre seg\u00fcent repte \u00e9s arribar a la fase II per poder provar la ter\u00e0pia amb molts m\u00e9s pacients\u201d. <\/p>\n
Paral\u00b7lelament, l\u2019equip de Buscail continua amb la recerca de biomarcadors que puguin ser \u00fatils per a nous tractaments de c\u00e0ncer de p\u00e0ncrees o per millorar-ne la diagnosi.<\/p>\n","protected":false},"excerpt":{"rendered":"
El gastroenter\u00f2leg de l\u2019Hospital Universitari de Rangueil, a Touluse, i investigador de l\u2019INSERM, Louis Buscail ha explicat els seus darrers aven\u00e7os en ter\u00e0pia g\u00e8nica contra el c\u00e0ncer de p\u00e0ncrees avan\u00e7at al cicle de seminaris IDIBELL el passat 11 de novembre. Actualment, l\u2019\u00fanic tractament eficient contra el c\u00e0ncer de p\u00e0ncrees \u00e9s la cirurgia. L\u2019agent quimioter\u00e0peutic gemcitabina […]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-25 19:23:48","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9594"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=9594"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9594\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=9594"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=9594"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=9594"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}