{"id":9587,"date":"2011-11-30T00:00:00","date_gmt":"2011-11-29T23:00:00","guid":{"rendered":"https:\/\/idibell.cat\/blog\/2011\/11\/30\/ferran-azorin-el-coneixement-dels-mecanismes-basics-de-lepigenetica-permetra-en-el-futur-desenvolupar-noves-estrategies-terapeutiques\/"},"modified":"2023-03-03T16:03:34","modified_gmt":"2023-03-03T15:03:34","slug":"ferran-azorin-el-coneixement-dels-mecanismes-basics-de-lepigenetica-permetra-en-el-futur-desenvolupar-noves-estrategies-terapeutiques","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2011\/11\/ferran-azorin-el-coneixement-dels-mecanismes-basics-de-lepigenetica-permetra-en-el-futur-desenvolupar-noves-estrategies-terapeutiques\/","title":{"rendered":"Ferran Azor\u00edn: \u201cEl coneixement dels mecanismes b\u00e0sics de l\u2019epigen\u00e8tica permetr\u00e0 en el futur desenvolupar noves estrat\u00e8gies terap\u00e8utiques\u201d"},"content":{"rendered":"<p>El laboratori de l\u2019<a href=\"http:\/\/www.ibmb.csic.es\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"enllac\">Institut de Biologia Molecular<\/span><\/a> del CSIC a Barcelona liderat per Ferran Azor\u00edn, centra la seva investigaci\u00f3 a intentar comprendre els mecanismes b\u00e0sics que regulen el funcionament del genoma a trav\u00e9s de l\u2019epigen\u00e8tica. L\u2019investigador ha explicat els seus darrers aven\u00e7os en aquest camp en el cicle de seminaris IDIBELL el 25 de novembre.<\/p>\n<p>Un dels factors epigen\u00e8tics que estudia l\u2019equip d\u2019Azor\u00edn \u00e9s la prote\u00efna H1, la menys coneguda de les histones, en <em>Drospohila melanogaster<\/em> (mosca del vinagre). \u201cL\u2019avantatge d\u2019aquest organisme \u00e9s que nom\u00e9s presenta una variant d\u2019H1 i fa m\u00e9s f\u00e0cil el seu estudi\u201d. L\u2019objectiu de la recerca \u00e9s, a trav\u00e9s de la gen\u00e8tica, la biologia molecular i la bioqu\u00edmica, comprendre quines funcions regula H1: \u201cel que hem vist \u00e9s que contribueix al manteniment de l\u2019estabilitat gen\u00f2mica i a altres aspectes com el desenvolupament de les c\u00e8l\u00b7lules germinals\u201d.<\/p>\n<p>Segons Azor\u00edn, l\u2019estudi de l\u2019epigen\u00e8tica ha evolucionat molt en els \u00faltims anys. \u201cAl principi en d\u00e8iem cromatina perqu\u00e8 nom\u00e9s en cone\u00edxiem els aspectes estructurals per\u00f2 cada vegada coneixem m\u00e9s la import\u00e0ncia que te en l\u2019estructuraci\u00f3 del genoma, com l\u2019epigen\u00e8tica regula la gen\u00e8tica&#8230; estem aprenent els mecanismes b\u00e0sics i acabarem entenent quines malalties estan associades a tot plegat de manera que ens permetr\u00e0 trobar, en el futur, noves estrat\u00e8gies terap\u00e8utiques\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>El laboratori de l\u2019Institut de Biologia Molecular del CSIC a Barcelona liderat per Ferran Azor\u00edn, centra la seva investigaci\u00f3 a intentar comprendre els mecanismes b\u00e0sics que regulen el funcionament del genoma a trav\u00e9s de l\u2019epigen\u00e8tica. L\u2019investigador ha explicat els seus darrers aven\u00e7os en aquest camp en el cicle de seminaris IDIBELL el 25 de novembre. [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":23132,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-09 21:06:02","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9587"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=9587"}],"version-history":[{"count":1,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9587\/revisions"}],"predecessor-version":[{"id":23133,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9587\/revisions\/23133"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/23132"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=9587"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=9587"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=9587"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}