Johns Hopkins University <\/span><\/a>(Baltimore, Estats Units), on va estudiar la relaci\u00f3 entre la metilaci\u00f3 de l\u2019ADN i el c\u00e0ncer. De fet, el seu treball ha estat decisiu per demostrar que tots els tumors humans tenen en com\u00fa una alteraci\u00f3 qu\u00edmica concreta: la hipermetilaci\u00f3 dels gens supressors de tumors.<\/p>\nLes seves aportacions, de notable originalitat, contribueixen a revisar i complementar paradigmes cient\u00edfics que es creien ben establerts, en demostrar la import\u00e0ncia de factors externs en la modificaci\u00f3 directa de gens amb efectes per a la seva regulaci\u00f3. La seva obra cient\u00edfica, de gran extensi\u00f3 malgrat la seva joventut, demostra com les modificacions epigen\u00e8tiques del material hereditari poden contribuir al desenvolupament dels processos d’envelliment i c\u00e0ncer. A m\u00e9s, ha suposat la base per a l’aprovaci\u00f3 recent d’alguns f\u00e0rmacs antitumorals i obre el cam\u00ed per con\u00e8ixer l’epigenoma hum\u00e0, un projecte internacional en qu\u00e8 Esteller ocupa un paper rellevant.<\/p>\n","protected":false},"excerpt":{"rendered":"
Manel Esteller, director del Programa de Epigen\u00e9tica i Biologia del C\u00e0ncer de l’DIBELL, Professor de Gen\u00e8tica de la Universitat de Barcelona i Professor d’Investigaci\u00f3 ICREA, ha estat escollit Acad\u00e8mic de la Real Acad\u00e8mia Nacional de Farm\u00e0cia (RANF) el passat 14 de Desembre. La Real Acad\u00e8mia Nacional de Farm\u00e0cia, fundada el 1589, \u00e9s una societat cient\u00edfica […]<\/p>\n","protected":false},"author":6,"featured_media":23121,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[376],"tags":[],"class_list":["post-9577","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-epigenetica-del-cancer"],"publishpress_future_action":{"enabled":false,"date":"2025-01-25 07:58:58","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9577","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=9577"}],"version-history":[{"count":2,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9577\/revisions"}],"predecessor-version":[{"id":23123,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9577\/revisions\/23123"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/23121"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=9577"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=9577"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=9577"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}