{"id":9528,"date":"2012-04-03T00:00:00","date_gmt":"2012-04-02T22:00:00","guid":{"rendered":"https:\/\/idibell.cat\/blog\/2012\/04\/03\/investigadors-de-lidibell-creen-una-aplicacio-informatica-que-permet-lanalisi-estadistica-en-linia-de-dades-dexpressio-de-gens\/"},"modified":"2022-09-09T16:44:51","modified_gmt":"2022-09-09T14:44:51","slug":"investigadors-de-lidibell-creen-una-aplicacio-informatica-que-permet-lanalisi-estadistica-en-linia-de-dades-dexpressio-de-gens","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2012\/04\/investigadors-de-lidibell-creen-una-aplicacio-informatica-que-permet-lanalisi-estadistica-en-linia-de-dades-dexpressio-de-gens\/","title":{"rendered":"Investigadors de l\u2019IDIBELL creen una aplicaci\u00f3 inform\u00e0tica que permet l\u2019an\u00e0lisi estad\u00edstica en l\u00ednia de dades d\u2019expressi\u00f3 de gens"},"content":{"rendered":"<p>La revista <a href=\"http:\/\/www.elsevier.com\/wps\/find\/journaldescription.cws_home\/351\/description\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"enllac\">Computers in Biology and Medicine<\/span><\/a> ha publicat un article sobre la nova aplicaci\u00f3 inform\u00e0tica BootstRatio, creada per investigadors de l&#8217;IDIBELL, que permet l\u2019an\u00e0lisi estad\u00edstica en l\u00ednia de dades d\u2019expressi\u00f3 de gens. L\u2019aplicaci\u00f3 \u00e9s accessible a trav\u00e9s de <a class=\"enllac\" href=\"http:\/\/regstattools.net\/br\">http:\/\/regstattools.net\/br<\/a> i ja l\u2019estan utilitzant cient\u00edfics d\u2019arreu del m\u00f3n.<\/p>\n<p>Els investigadors del grup de recerca de Gen\u00e8tica Molecular Humana de l\u2019IDIBELL, liderat per Virginia Nunes, es trobaven amb un problema a l\u2019hora de dotar de significaci\u00f3 els resultats de les an\u00e0lisis estad\u00edstiques de les dades d\u2019expressi\u00f3 de gens. La majoria dels c\u00e0lculs estad\u00edstics que es fan per comparar dades d\u2019expressi\u00f3 de gens pressuposen una distribuci\u00f3 normal d\u2019aquestes dades i aquesta distribuci\u00f3 no sempre \u00e9s real.<\/p>\n<p>A partir d\u2019aquest problema i juntament amb Ramon Cl\u00e8ries, expert en estad\u00edstica del grup de Prevenci\u00f3 i Control del C\u00e0ncer de l\u2019IDIBELL, van decidir treballar en una an\u00e0lisi estad\u00edstica que, utilitzant t\u00e8cniques de remostreig permet\u00e9s generar una distribuci\u00f3 hipot\u00e8tica de les dades sense partir de cap distribuci\u00f3 inicial, i que expos\u00e9s les dades en un llenguatge comprensible per al cient\u00edfic.<\/p>\n<p>Aix\u00ed neix l\u2019aplicaci\u00f3 BootstRatio a la qual es pot accedir des d\u2019un servidor remot. \u201cS\u2019hi introdueixen les dades i en pocs temps el programa envia els resultats per correu electr\u00f2nic en un llenguatge comprensible per al cient\u00edfic\u201d, ha explicat Miguel L\u00f3pez de Heredia, investigador <a href=\"http:\/\/www.ciberer.es\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"enllac\">CIBERER<\/span><\/a> del grup de recerca de Gen\u00e8tica Molecular Humana de l\u2019IDIBELL. \u201cEls estad\u00edstics i els bi\u00f2legs de vegades parlem llenguatges diferents. Aquesta nova eina permet una interpretaci\u00f3 biol\u00f2gica dels resultats de l\u2019an\u00e0lisi estad\u00edstica\u201d. Cl\u00e8ries ha explicat que l\u2019aplicaci\u00f3 BootstRatio \u201c\u00e9s molt senzilla d\u2019utilitzar i no requereix especialitzaci\u00f3 estad\u00edstica\u201d.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Refer\u00e8ncia de l\u2019article<\/strong><\/p>\n<p>Cl\u00e8ries R., Galvez J., Espino M., Ribes J., Nunes V. and L\u00f3pez de Heredia M. BootsRatio: A web-based statistical analysis of fold-change in qPCR and RT-qPCR data using resampling methods. Computers in Biology and Medicine 42 (2012) 438-445. doi: 10.1016\/j.compbiomed.2011.12-012 <strong><\/p>\n<p><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>La revista Computers in Biology and Medicine ha publicat un article sobre la nova aplicaci\u00f3 inform\u00e0tica BootstRatio, creada per investigadors de l&#8217;IDIBELL, que permet l\u2019an\u00e0lisi estad\u00edstica en l\u00ednia de dades d\u2019expressi\u00f3 de gens. L\u2019aplicaci\u00f3 \u00e9s accessible a trav\u00e9s de http:\/\/regstattools.net\/br i ja l\u2019estan utilitzant cient\u00edfics d\u2019arreu del m\u00f3n. Els investigadors del grup de recerca de [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":22159,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[332,396,334,454,464,373],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-10 06:15:20","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9528"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=9528"}],"version-history":[{"count":2,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9528\/revisions"}],"predecessor-version":[{"id":22160,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9528\/revisions\/22160"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/22159"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=9528"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=9528"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=9528"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}