{"id":9524,"date":"2012-04-13T00:00:00","date_gmt":"2012-04-12T22:00:00","guid":{"rendered":"https:\/\/idibell.cat\/blog\/2012\/04\/13\/oriol-casanovas-opina-sobre-les-limitacions-de-les-terapies-antiangiogeniques-a-nature\/"},"modified":"2022-09-09T16:20:24","modified_gmt":"2022-09-09T14:20:24","slug":"oriol-casanovas-opina-sobre-les-limitacions-de-les-terapies-antiangiogeniques-a-nature","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2012\/04\/oriol-casanovas-opina-sobre-les-limitacions-de-les-terapies-antiangiogeniques-a-nature\/","title":{"rendered":"Oriol Casanovas opina sobre les limitacions de les ter\u00e0pies antiangiog\u00e8niques a Nature"},"content":{"rendered":"<p>L\u2019investigador de l\u2019IDIBELL Oriol Casanovas publica en el darrer n\u00famero de la revista <a href=\"http:\/\/www.nature.com\/nature\/journal\/v484\/n7392\/index.html\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"enllac\"><span class=\"enllac\">Nature<\/span><\/span><\/a> un article que sota el t\u00edtol \u201cLimitations of therapies exposed\u201d destaca la necessitat de con\u00e8ixer les limitacions de la ter\u00e0pies antiangiog\u00e8niques per obrir portes a noves combinacions o aproximacions terap\u00e8utiques que impliquin majors beneficis per als pacients.<\/p>\n<p>En concret, Casanovas comenta dues publicacions recents on s\u2019exposen les limitacions cl\u00edniques de determinats tractaments. Per una banda, la combinaci\u00f3 d\u2019antiangiog\u00e8nics i quimioter\u00e0pia, un tractament molt utilitzat per\u00f2 que t\u00e9 com a limitaci\u00f3 que el f\u00e0rmac antiangiog\u00e8nic al frenar el creixement dels vasos sanguinis del tumor tamb\u00e9 evita que hi arribi la quimioter\u00e0pia. I per l\u2019altra, l\u2019\u00fas d\u2019un f\u00e0rmac antiangiog\u00e8nic que redueix els tumors de mama per\u00f2 no acaba amb les c\u00e8l\u00b7lules mares tumorals que a m\u00e9s augmenten en n\u00famero, fent que el tumor que queda sigui m\u00e9s agressiu i de pitjor pron\u00f2stic.<\/p>\n<p>Per Casanovas \u201cest\u00e0 clar que els tractaments antiangiog\u00e8nics s\u00f3n efectius per\u00f2 hem d\u2019entendre les limitacions que tenen per qu\u00e8 nom\u00e9s aix\u00ed podrem buscar noves combinacions, seq\u00fcenciar-les de forma diferent.. o altres innovacions que puguin suposar un millor benefici per al pacient\u201d.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Refer\u00e8ncia de l&#8217;article<\/strong><\/p>\n<p>Oriol Casanovas. Limitations of Therapies exposed. Nature. Vol 484 (44-46). 5 April 2012<\/p>\n","protected":false},"excerpt":{"rendered":"<p>L\u2019investigador de l\u2019IDIBELL Oriol Casanovas publica en el darrer n\u00famero de la revista Nature un article que sota el t\u00edtol \u201cLimitations of therapies exposed\u201d destaca la necessitat de con\u00e8ixer les limitacions de la ter\u00e0pies antiangiog\u00e8niques per obrir portes a noves combinacions o aproximacions terap\u00e8utiques que impliquin majors beneficis per als pacients. En concret, Casanovas comenta [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":22148,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[397,332,447,452],"tags":[],"class_list":["post-9524","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-angiogenesi-tumoral","category-cancer","category-p-de-mecanismes-molelculars-i-terapia-experimental-en-oncologia-oncobell","category-procure"],"publishpress_future_action":{"enabled":false,"date":"2024-12-30 06:40:19","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9524","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=9524"}],"version-history":[{"count":2,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9524\/revisions"}],"predecessor-version":[{"id":22150,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/9524\/revisions\/22150"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/22148"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=9524"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=9524"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=9524"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}