El cap de la Unitat de Gen\u00e8tica Molecular de l’Hospital Universitari de Valdecilla, Santander, Jos\u00e9 Luis Fern\u00e1ndez-Lluna ha explicat el 1 de mar\u00e7 els seus \u00faltims avan\u00e7os en la investigaci\u00f3 de c\u00e8l\u00b7lules mare tumorals de glioblastoma, el tumor cerebral m\u00e9s agressiu, en una confer\u00e8ncia enel marc del cicle de seminaris IDIBELL.<\/p>\n
Les t\u00e8cniques de neurocirurgia han millorat molt en els \u00faltims anys. Tot i aix\u00f2, actualment \u00e9s impossible evitar les recaigudes del glioblastoma ja qu\u00e8 segons ha explicat Jos\u00e9 Luis Fern\u00e1ndez-Lluna, existeix una zona peritumoral infectada amb c\u00e8l\u00b7lules mare tumorals que no es pot extirpar perqu\u00e8 \u00e9s teixit normal del cervell. Aquesta poblaci\u00f3 de c\u00e8l\u00b7lules mare tumorals t\u00e9 una gran capacitat per a migrar dintre del cervell\u201d.<\/p>\n
Fern\u00e1ndez-Lluna ha explicat com han identificat aquestes c\u00e8l\u00b7lules mare tumorals i el seu treball actual que es basa ara a seguir investigant els mecanismes d’invasi\u00f3 i identificar noves dianes terap\u00e8utiques que puguin bloquejar-los.<\/p>\n
\u201cActualment, estem provant en ratolins un inhibidor de la ruta NFKb que duu a aquestes c\u00e8l\u00b7lules mare a la senesc\u00e8ncia i, en col\u00b7laboraci\u00f3 amb una plataforma bioinform\u00e0tica, estem buscant entre m\u00e9s de cinc milions de compostos, nous candidats a actuar sobre diverses dianes terap\u00e8utiques\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"
El cap de la Unitat de Gen\u00e8tica Molecular de l’Hospital Universitari de Valdecilla, Santander, Jos\u00e9 Luis Fern\u00e1ndez-Lluna ha explicat el 1 de mar\u00e7 els seus \u00faltims avan\u00e7os en la investigaci\u00f3 de c\u00e8l\u00b7lules mare tumorals de glioblastoma, el tumor cerebral m\u00e9s agressiu, en una confer\u00e8ncia enel marc del cicle de seminaris IDIBELL. Les t\u00e8cniques de neurocirurgia […]<\/p>\n","protected":false},"author":6,"featured_media":20571,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[491,493],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-11 01:42:34","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8583"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=8583"}],"version-history":[{"count":1,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8583\/revisions"}],"predecessor-version":[{"id":20572,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8583\/revisions\/20572"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/20571"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=8583"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=8583"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=8583"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}