El catedr\u00e0tic de Medicina Legal i director del grup de medicina gen\u00f2mica de la Universitat de Santiago de Compostela, \u00c1ngel Carracedo va parlar dels reptes de futur de la farmacogen\u00e8tica en l\u2019\u00e0mbit de la cl\u00ednica. Va ser el passat 15 de mar\u00e7 en una confer\u00e8ncia dins el marc dels seminaris IDIBELL.<\/p>\n
Actualment nom\u00e9s un 50% dels f\u00e0rmacs de primera l\u00ednia s\u00f3n efectius i els efectes adversos dels f\u00e0rmacs s\u00f3n la quarta causa de mort als Estats Units i la vuitena a Europa. Segons ha explicat \u00c1ngel Carracedo \u201cdos individus no responen igual a un f\u00e0rmac ni en condicions de salut ni, molt menys, en condicions de malaltia. Un dels factors que determinen aquesta resposta \u00e9s la gen\u00e8tica\u201d.<\/p>\n
Con\u00e8ixer la gen\u00e8tica del pacient podria permetre administrar-li nom\u00e9s els medicaments adequats i estalviar-li els efectes adversos d\u2019aquells f\u00e0rmacs que no li serien efica\u00e7os. De fet, segons ha explicat Carracedo, la FDA i l\u2019EMEA (les ag\u00e8ncies reguladores dels medicaments als Estats Units i a Europa respectivament) ja ha fet diverses recomanacions en la fitxa t\u00e8cnica de diversos f\u00e0rmacs, especialment de quimioter\u00e0pia, de forma que sigui obligatori l\u2019an\u00e0lisi gen\u00e8tic abans de la seva prescripci\u00f3.<\/p>\n
Carracedo ha advertit per\u00f2 que \u201cno a tots els cl\u00ednics els arriba aquesta informaci\u00f3 i que no sempre s\u2019utilitza de manera adequada\u201d. \u201cHem de seguir treballant\u201d ha dit Carracedo \u201cen la validaci\u00f3 de nous biomarcadors que tinguin una relaci\u00f3 despesa\/efic\u00e0cia assumible i trobar la manera d\u2019implementar la farmacogen\u00e8tica de la manera m\u00e9s eficient a la pr\u00e0ctica cl\u00ednica\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"
El catedr\u00e0tic de Medicina Legal i director del grup de medicina gen\u00f2mica de la Universitat de Santiago de Compostela, \u00c1ngel Carracedo va parlar dels reptes de futur de la farmacogen\u00e8tica en l\u2019\u00e0mbit de la cl\u00ednica. Va ser el passat 15 de mar\u00e7 en una confer\u00e8ncia dins el marc dels seminaris IDIBELL. Actualment nom\u00e9s un 50% […]<\/p>\n","protected":false},"author":6,"featured_media":20549,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[491,493],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-11 16:29:13","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8576"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=8576"}],"version-history":[{"count":3,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8576\/revisions"}],"predecessor-version":[{"id":20552,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8576\/revisions\/20552"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/20549"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=8576"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=8576"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=8576"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}