El camp d’estudi de Piero Crespo de l’Institut de Biomedicina i Biotecnologia de Cant\u00e0bria (IBBTEC) \u00e9s la regulaci\u00f3 dels senyals Ras-ERK. El 19 d’abril va explicar els \u00faltims avan\u00e7os de la seva investigaci\u00f3 en una confer\u00e8ncia emmarcada en el cicle de seminaris IDIBELL.<\/p>\n
El seu treball se centra en l’estudi dels mecanismes de regulaci\u00f3 de Ras en particular en com la localitzaci\u00f3 subcel\u00b7lular i el confinament dels senyals incideixen en les funcions biol\u00f2giques i bioqu\u00edmiques d’aquestes prote\u00efnes, tant en contextos fisiol\u00f2gics com patol\u00f2gics.<\/p>\n
Segons Piero Crespo \u201cla ruta de senyalitzaci\u00f3 Ras-ERK est\u00e0 activada aproximadament en el 50% dels tumors humans. Nosaltres estem buscant nous tipus de f\u00e0rmacs per a bloquejar els senyals que flueixen a trav\u00e9s d’aquesta via de senyalitzaci\u00f3\u201d.<\/p>\n
\u201cEns interessa trobar dos tipus d’inhibidors\u201d ha explicat Crespo \u201cd’una banda, que actu\u00efn lloc-espec\u00edficament bloquejant subsenyals en lloc del senyal total, i per altre trobar inhibidors que funcionin mitjan\u00e7ant el bloqueig prote\u00efna-prote\u00efna en comptes d’inhibir l’activitat catab\u00f2lica de les prote\u00efnes involucrades en la ruta Ras-ERK\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"
El camp d’estudi de Piero Crespo de l’Institut de Biomedicina i Biotecnologia de Cant\u00e0bria (IBBTEC) \u00e9s la regulaci\u00f3 dels senyals Ras-ERK. El 19 d’abril va explicar els \u00faltims avan\u00e7os de la seva investigaci\u00f3 en una confer\u00e8ncia emmarcada en el cicle de seminaris IDIBELL. El seu treball se centra en l’estudi dels mecanismes de regulaci\u00f3 de […]<\/p>\n","protected":false},"author":6,"featured_media":20411,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[1,491,493],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-09 15:18:32","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8564"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=8564"}],"version-history":[{"count":1,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8564\/revisions"}],"predecessor-version":[{"id":20412,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8564\/revisions\/20412"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/20411"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=8564"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=8564"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=8564"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}