El catedr\u00e0tic de microbiologia i investigador del grup de Gen\u00e8tica de microbacteris de la Universitat de Saragossa, Carlos Mart\u00edn, ha explicat en quina fase es troben els primers assajos de la MTBVAC. La confer\u00e8ncia celebrada el 7 de juny s’emmarca en el cicle de seminaris IDIBELL.<\/p>\n
Mart\u00edn ha explicat el proc\u00e9s de creaci\u00f3 de la vacuna, la primera amb bacil atenuat de tuberculosi i com al principi va resultar dif\u00edcil perqu\u00e8 “ning\u00fa creia que una soca atenuada pogu\u00e9s arribar a la cl\u00ednica”. L’investigador explica que es van haver de complir els requisits pactats a Ginebra per l’\u00fas de vacunes vives, \u00e9s a dir les soques han de presentar dues modificacions gen\u00e8tiques perqu\u00e8 no pugui recuperar la virul\u00e8ncia.<\/p>\n
La MTBVAC \u00e9s una vacuna que busca activar el sistema immunitari perqu\u00e8 sigui capa\u00e7 de recon\u00e8ixer l’agent infecci\u00f3s i protegeixi a llarg termini enfront de la forma m\u00e9s comuna de la malaltia: la respirat\u00f2ria. L’actual vacuna BCG protegeix contra diferents formes de tuberculosi en nens, per\u00f2 la seva protecci\u00f3 en tuberculosi pulmonar d’adults \u00e9s molt variable.<\/p>\n
La idea de Carlos Mart\u00edn \u00e9s que aquesta nova vacuna pugui substituir BCG. “Necessitem que tingui una resposta millor i el llist\u00f3 est\u00e0 molt alt”. Actualment, la vacuna de Mart\u00edn est\u00e0 en fase I d’assaig cl\u00ednic per comprovar la seguretat i la immunogenicitat en el Complex Hospitalari de la Universitat de Vaudois (Lausana, Su\u00efssa).<\/p>\n","protected":false},"excerpt":{"rendered":"
El catedr\u00e0tic de microbiologia i investigador del grup de Gen\u00e8tica de microbacteris de la Universitat de Saragossa, Carlos Mart\u00edn, ha explicat en quina fase es troben els primers assajos de la MTBVAC. La confer\u00e8ncia celebrada el 7 de juny s’emmarca en el cicle de seminaris IDIBELL. Mart\u00edn ha explicat el proc\u00e9s de creaci\u00f3 de la […]<\/p>\n","protected":false},"author":6,"featured_media":19839,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1,491,493],"tags":[],"class_list":["post-8534","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sin-categorizar","category-divulgacio-i-educacio","category-innovacio"],"publishpress_future_action":{"enabled":false,"date":"2025-03-02 13:38:13","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8534","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=8534"}],"version-history":[{"count":1,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8534\/revisions"}],"predecessor-version":[{"id":19840,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8534\/revisions\/19840"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/19839"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=8534"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=8534"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=8534"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}