{"id":8522,"date":"2013-07-11T00:00:00","date_gmt":"2013-07-10T22:00:00","guid":{"rendered":"https:\/\/idibell.cat\/blog\/2013\/07\/11\/el-virus-del-papil%c2%b7loma-huma-multiplica-el-risc-de-patir-cancer-oral\/"},"modified":"2021-11-18T12:42:12","modified_gmt":"2021-11-18T11:42:12","slug":"el-virus-del-papilloma-huma-multiplica-el-risc-de-patir-cancer-oral","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2013\/07\/el-virus-del-papilloma-huma-multiplica-el-risc-de-patir-cancer-oral\/","title":{"rendered":"El virus del papil\u00b7loma hum\u00e0 multiplica el risc de patir c\u00e0ncer oral"},"content":{"rendered":"<p><strong>El VPH 16, un dels tipus de VPH m\u00e9s agressius, est\u00e0 present en m\u00e9s del 30% dels pacients amb c\u00e0ncer d\u2019orofaringe i en menys d\u2019un 1% de les persones sanes<\/strong> La pres\u00e8ncia del virus del papil\u00b7loma hum\u00e0 (VPH) pot arribar a multiplicar per 130 el risc de desenvolupar un tumor de la orofaringe. Aix\u00ed ho conclou un estudi publicat a la revista Journal of the National Cancer Institute, en el qual ha participat Xavier Castellsagu\u00e9, investigador del grup de virus i c\u00e0ncer de l&#8217;IDIBELL i del Programa de Recerca en Epidemiologia del C\u00e0ncer de l\u2019Institut Catal\u00e0 d\u2019Oncologia.<\/p>\n<p><strong>Anticossos de VPH en sang<\/strong> <strong><br \/>\n<\/strong>L\u2019estudi forma part del projecte europeu ARCAGE, i ha comparat la pres\u00e8ncia en sang d\u2019anticossos contra el VPH en 1.425 persones sanes i en 1.496 pacients amb c\u00e0ncer del tracte aero-digestiu (cavitat oral, faringe, laringe, es\u00f2fag).<\/p>\n<p>Les conclusions indiquen que la pres\u00e8ncia del VPH, en concret del VPH16, augmenta molt significativament el risc de desenvolupar el tumor maligne de la orofaringe.<\/p>\n<p>En el grup de persones sanes, el VPH 16, nom\u00e9s era present en el 0\u20198% dels casos, mentre que en el grup de malalts, el percentatge arribava al 30\u20192%. Aix\u00ed mateix, la pres\u00e8ncia de dos anticossos del VPH16, el E6 i el E7, \u00e9s molt poc freq\u00fcent en persones sanes (1 cas de 1425) i arriba a multiplicar per 800 el risc de desenvolupar la malaltia quan es detecten els dos simult\u00e0niament.<\/p>\n<p><strong>El VPH, responsable de m\u00e9s de 5% dels c\u00e0ncers<\/strong> <strong><br \/>\n<\/strong>La infecci\u00f3 pel VPH \u00e9s la infecci\u00f3 de transmissi\u00f3 sexual m\u00e9s comuna a tot el m\u00f3n: al llarg de la vida, m\u00e9s del 80% de les dones sexualment actives n\u2019hauran estat exposades. La fam\u00edlia del VPH compta amb m\u00e9s de 150 genotips (tipus virals), uns 15 dels quals s\u00f3n d\u2019alt risc de promoure c\u00e0ncer. La infecci\u00f3 per un d\u2019aquests tipus d\u2019alt risc t\u00e9 una durada mitjana de 8-12 mesos i, en els casos m\u00e9s severs, pot arribar als dos anys. El VPH \u00e9s conegut per ser el responsable del c\u00e0ncer de coll d\u2019\u00fater i d\u2019altres tumors com els de vulva, vagina, penis, anus&#8230; Darrerament s\u2019ha demostrat que tamb\u00e9 est\u00e0 darrera de fins al 35 per cent dels tumors d\u2019orofaringe. Aquest tumor \u00e9s relativament poc freq\u00fcent, i est\u00e0 fortament associat al consum de tabac i d&#8217;alcohol. La incid\u00e8ncia ha augmentat en les \u00faltimes d\u00e8cades en moltes parts del m\u00f3n, especialment a Europa i Am\u00e8rica del Nord. Aquest increment es creu que \u00e9s producte del creixent nombre d&#8217;infeccions pel virus del papil\u00b7loma hum\u00e0 (VPH) com a conseq\u00fc\u00e8ncia de l\u2019expansi\u00f3 de determinades pr\u00e0ctiques sexuals, especialment el sexe oral.<\/p>\n<p><strong>Detecci\u00f3 preco\u00e7 per a un millor pron\u00f2stic<\/strong> <strong><br \/>\n<\/strong>Un altre article publicat recentment a la revista Journal of Clinical Oncology en el qual tamb\u00e9 ha participat l\u2019ICO, mostra que un ter\u00e7 de les persones que van desenvolupar un c\u00e0ncer d\u2019orofaringe tenien anticossos contra el VPH fins a 12 anys abans de l\u2019aparici\u00f3 de la malaltia, cosa que nom\u00e9s passava en menys d\u2019un u per cent dels participants que no van desenvolupar el tumor. Aix\u00ed doncs, un test del VPH podria facilitar la detecci\u00f3 preco\u00e7 del c\u00e0ncer oral provocat pel virus anys abans de l\u2019aparici\u00f3 de la malaltia<\/p>\n","protected":false},"excerpt":{"rendered":"<p>El VPH 16, un dels tipus de VPH m\u00e9s agressius, est\u00e0 present en m\u00e9s del 30% dels pacients amb c\u00e0ncer d\u2019orofaringe i en menys d\u2019un 1% de les persones sanes La pres\u00e8ncia del virus del papil\u00b7loma hum\u00e0 (VPH) pot arribar a multiplicar per 130 el risc de desenvolupar un tumor de la orofaringe. Aix\u00ed ho [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":19812,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1,332,337,454],"tags":[],"class_list":["post-8522","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sin-categorizar","category-cancer","category-infeccions-i-cancer","category-p-depidemiologia-salut-publica-prevencio-del-cancer-i-cures-palliatives"],"publishpress_future_action":{"enabled":false,"date":"2025-01-25 09:12:07","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8522","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=8522"}],"version-history":[{"count":2,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8522\/revisions"}],"predecessor-version":[{"id":19813,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8522\/revisions\/19813"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/19812"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=8522"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=8522"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=8522"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}