{"id":8500,"date":"2013-10-09T00:00:00","date_gmt":"2013-10-08T22:00:00","guid":{"rendered":"https:\/\/idibell.cat\/blog\/2013\/10\/09\/experts-en-cel%c2%b7lules-beta-es-reuneixen-a-sitges-per-analitzar-noves-estrategies-contra-la-diabetis\/"},"modified":"2021-11-17T16:03:48","modified_gmt":"2021-11-17T15:03:48","slug":"experts-en-cellules-beta-es-reuneixen-a-sitges-per-analitzar-noves-estrategies-contra-la-diabetis","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2013\/10\/experts-en-cellules-beta-es-reuneixen-a-sitges-per-analitzar-noves-estrategies-contra-la-diabetis\/","title":{"rendered":"Experts en c\u00e8l\u00b7lules beta es reuneixen a Sitges per analitzar noves estrat\u00e8gies contra la diabetis"},"content":{"rendered":"<p>Despr\u00e9s de la 49a <a class=\"external\" title=\"EASD Barcelona 2013\" href=\"http:\/\/www.idibaps.org\/actualitat\/noticies\/12977\/els-avencos-en-investigacio-clinica-i-basica-en-diabetis-es-donen-cita-a-barcelona\" target=\"_blank\" rel=\"external noopener noreferrer\">Reuni\u00f3 Anual<\/a> de l&#8217;Associaci\u00f3 Europea per a l&#8217;Estudi de la Diabetis (European Association for the Study of Diabetes, EASD), que ens va portar uns 20.000 diabet\u00f2legs a Barcelona fins el 27 de setembre, s\u2019ha celebrat un <a class=\"external\" title=\"ISG 2013\" href=\"http:\/\/www.isg2013.org\/\" target=\"_blank\" rel=\"external noopener noreferrer\">Simposi<\/a> sobre els darrers aven\u00e7os en els camp de la medicina regenerativa i la regulaci\u00f3 gen\u00f2mica de les c\u00e8l\u00b7lules beta pancre\u00e0tiques. Els coordinadors del Simposi van ser el Dr.<strong> Eduard Montanya<\/strong>, de l\u2019IDIBELL-UB, i el Dr. <strong>Jorge Ferrer<\/strong>, de l\u2019IDIBAPS i l\u2019<em>Imperial College London<\/em>.<\/p>\n<p>La regeneraci\u00f3 de les c\u00e8l\u00b7lules beta pancre\u00e0tiques \u00e9s una opci\u00f3 terap\u00e8utica contra la diabetis que podria millorar la malaltia de molts pacients que actualment es tracten amb injeccions d\u2019insulina. Per aix\u00f2 un dels principals reptes que es van discutir a la reuni\u00f3 van ser les noves formes d\u2019obtenci\u00f3 de c\u00e8l\u00b7lules beta. Algunes de les possibilitats m\u00e9s avan\u00e7ades s\u00f3n la regeneraci\u00f3 de c\u00e8l\u00b7lules beta a partir de progenitors end\u00f2gens, la regeneraci\u00f3 a trav\u00e9s de transdiferenciaci\u00f3 d\u2019altres tipus de c\u00e8l\u00b7lules pancre\u00e0tiques o la diferenciaci\u00f3 a partir de c\u00e8l\u00b7lules mare. Tamb\u00e9 s\u2019est\u00e0 intentant diferenciar altres teixits cap a c\u00e8l\u00b7lules beta. Tots aquests m\u00e8todes persegueixen obtenir una quantitat il\u00b7limitada de c\u00e8l\u00b7lules per trasplantar. El trasplantament de c\u00e8l\u00b7lules beta productores d\u2019insulina ja es practica en casos molt complicats de diabetis, per\u00f2 el teixit procedent de donants difunts \u00e9s molt esc\u00e0s.<\/p>\n<p>L\u2019altre \u00e0mbit de recerca protagonista va ser l\u2019estudi de la regulaci\u00f3 del genoma de les c\u00e8l\u00b7lules productores d\u2019insulina. Aquest camp t\u00e9 implicacions per la medicina regenerativa, ja que si es manipulen les instruccions del genoma es pot arribar a controlar la diferenciaci\u00f3 cel\u00b7lular. Tamb\u00e9 permet comprendre els resultats dels estudis GWAS (<em>Genome-Wide Association Studies<\/em>) que permeten analitzar en detall les susceptibilitats gen\u00e8tiques que permetran facilitar una ter\u00e0pia personalitzada per malalts amb diabetis mellitus. En el Simposi es van presentar estudis no publicats que demostren com mutacions o variants de seq\u00fc\u00e8ncies del genoma que afecten la regulaci\u00f3 gen\u00f2mica de certs gens donen lloc a diabetis o obesitat.<\/p>\n<p>La reuni\u00f3 va ser tot un \u00e8xit, fins al punt que va caler reobrir les inscripcions per donar cabuda als m\u00e9s de 200 professionals que van assistir-hi provinents d\u2019Europa, EEUU, Jap\u00f3, Australia i Sud \u00c0frica. Entre els participants de tot el m\u00f3n hi havia representants de l\u2019entorn de la recerca b\u00e0sica i tamb\u00e9 de la recerca cl\u00ednica, ja que es tracta d\u2019un camp molt transversal i translacional. La celebraci\u00f3 d\u2019aquest esdeveniment va ser possible gr\u00e0cies a esp\u00f2nsors destacats com Lilly, Novo Nordisk i Sanofi.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Despr\u00e9s de la 49a Reuni\u00f3 Anual de l&#8217;Associaci\u00f3 Europea per a l&#8217;Estudi de la Diabetis (European Association for the Study of Diabetes, EASD), que ens va portar uns 20.000 diabet\u00f2legs a Barcelona fins el 27 de setembre, s\u2019ha celebrat un Simposi sobre els darrers aven\u00e7os en els camp de la medicina regenerativa i la regulaci\u00f3 [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":19734,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[1,463,334,461],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-27 01:27:09","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8500"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=8500"}],"version-history":[{"count":2,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8500\/revisions"}],"predecessor-version":[{"id":19736,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/8500\/revisions\/19736"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/19734"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=8500"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=8500"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=8500"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}