{"id":7701,"date":"2018-02-01T00:00:00","date_gmt":"2018-01-31T23:00:00","guid":{"rendered":"https:\/\/idibell.cat\/blog\/2018\/02\/01\/alex-vaquero-rep-200-000-euros-de-worldwide-cancer-research-per-entendre-lorigen-del-cancer\/"},"modified":"2020-05-13T19:46:33","modified_gmt":"2020-05-13T17:46:33","slug":"alex-vaquero-rep-200-000-euros-de-worldwide-cancer-research-per-entendre-lorigen-del-cancer","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2018\/02\/alex-vaquero-rep-200-000-euros-de-worldwide-cancer-research-per-entendre-lorigen-del-cancer\/","title":{"rendered":"\u00c0lex Vaquero rep 200.000 euros de Worldwide Cancer Research per entendre l\u2019origen del c\u00e0ncer"},"content":{"rendered":"<table cellpadding=\"3\" width=\"100%\">\n<tbody>\n<tr>\n<td>\n<p>El doctor \u00c0lex Vaquero, l\u00edder del grup de recerca en biologia de la cromatina de l\u2019Institut d\u2019Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL), ha rebut un dels prestigiosos ajuts de l\u2019organitzaci\u00f3\u00a0<em>Worldwide Cancer Research\u00a0<\/em>per valor de 200.000 euros. L\u2019import servir\u00e0 per finan\u00e7ar un nou projecte d\u2019aquest grup de recerca b\u00e0sica centrat en l\u2019estudi dels mecanismes de formaci\u00f3 de tumors.<\/p>\n<p>\u00a0<\/p>\n<p>El projecte liderat pel Dr. Vaquero, titulat \u201c<em>Dissecting the specific contribution of Sirtuin ADP-ribosyltransferase and deacetylase activities in tumorigenesis<\/em>\u201d (Disseccionant la contribuci\u00f3 espec\u00edfica de la sirtuina ADP-ribosiltransferasa i la deacetilasa en la tumorig\u00e8nesi), tindr\u00e0 una durada de 36 mesos a partir d\u2019aquest mes de febrer. La recerca busca entendre el pes que un grup espec\u00edfic de prote\u00efnes, anomenades sirtuines, t\u00e9 en el desenvolupament del c\u00e0ncer per tal de proposar millores en el tractament d\u2019aquesta malaltia.<\/p>\n<p>\u00a0<\/p>\n<p>Les sirtuines s\u00f3n enzims implicats en la resposta cel\u00b7lular a l\u2019estr\u00e8s. Determinades condicions d&#8217;estr\u00e8s s\u00f3n molt rellevants, ja que s&#8217;han demostrat que contribueixen al desenvolupament de tumors. No obstant, el rol de les sirtuines \u00e9s complex, fet que es deu, en part, al fet que algunes sirtuines mostren dues activitats enzim\u00e0tiques diferents, en certs casos oposades. L\u2019equip del Dr. Vaquero vol entendre aquesta diversitat enzim\u00e0tica i la contribuci\u00f3 espec\u00edfica de cadascuna d&#8217;aquestes activitats al paper de les sirtuines en el c\u00e0ncer.<\/p>\n<p>\u00a0<\/p>\n<p>\u201cL\u2019ajut financer rebut servir\u00e0 principalment per a contractar un investigador post-doctoral que es dedicar\u00e0 en exclusiva a aquest projecte\u201d, comenta el Dr. Vaquero. Enguany, la convocat\u00f2ria d\u2019ajudes ha rebut 750 propostes, de les quals nom\u00e9s una vintena (un 3%) han estat seleccionades, incloent el projecte del grup IDIBELL.<\/p>\n<p>\u00a0<\/p>\n<p>La Worldwide Cancer Research (antiga AICR) \u00e9s una organitzaci\u00f3 ben\u00e8fica que finan\u00e7a la recerca de qualsevol tipus de c\u00e0ncer a nivell internacional a trav\u00e9s d\u2019una convocat\u00f2ria d\u2019ajudes anual de gran prestigi. L\u2019objectiu d\u2019aquesta organitzaci\u00f3 \u00e9s reclutar el millor talent investigador d\u2019arreu del m\u00f3n per desenvolupar tractaments contra el c\u00e0ncer millors i m\u00e9s efectius.<\/p>\n<\/td>\n<\/tr>\n<tr><\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>El doctor \u00c0lex Vaquero, l\u00edder del grup de recerca en biologia de la cromatina de l\u2019Institut d\u2019Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL), ha rebut un dels prestigiosos ajuts de l\u2019organitzaci\u00f3\u00a0Worldwide Cancer Research\u00a0per valor de 200.000 euros. L\u2019import servir\u00e0 per finan\u00e7ar un nou projecte d\u2019aquest grup de recerca b\u00e0sica centrat en l\u2019estudi dels mecanismes de formaci\u00f3 de [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":10614,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[376],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-11 17:53:23","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/7701"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=7701"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/7701\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/10614"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=7701"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=7701"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=7701"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}