{"id":7613,"date":"2018-07-09T00:00:00","date_gmt":"2018-07-08T22:00:00","guid":{"rendered":"https:\/\/idibell.cat\/blog\/2018\/07\/09\/nous-llibres-dautors-idibell-cancer-colorrectal-hereditari-i-genetica-de-les-cel%c2%b7lules-mare\/"},"modified":"2020-05-13T19:46:20","modified_gmt":"2020-05-13T17:46:20","slug":"nous-llibres-dautors-idibell-cancer-colorrectal-hereditari-i-genetica-de-les-cel%c2%b7lules-mare","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2018\/07\/nous-llibres-dautors-idibell-cancer-colorrectal-hereditari-i-genetica-de-les-cel%c2%b7lules-mare\/","title":{"rendered":"Nous llibres d&#8217;autors IDIBELL: c\u00e0ncer colorrectal hereditari i gen\u00e8tica de les c\u00e8l\u00b7lules mare"},"content":{"rendered":"<h2 style=\"margin: 0cm 0cm 10pt\"><span style=\"font-size:11pt\"><span style=\"line-height:115%\"><span style=\"font-family:Calibri,sans-serif\"><b>Hereditary Colorectal Cancer. Genetic Basis and Clinical Implications<\/b><\/span><\/span><\/span><\/h2>\n<p style=\"margin:0cm 0cm 10pt\"><span style=\"font-size:11pt\"><span style=\"line-height:115%\"><span style=\"font-family:Calibri,sans-serif\">Els Drs Laura Valle i Gabriel Capell\u00e1, investigadors del Programa de C\u00e0ncer Hereditari de l&#8217;Institut Catal\u00e0 d&#8217;Oncologia, IDIBELL (Oncobell), al costat del Dr. Stephen B. Gruber, del Norris Comprehensive Cancer Center (Universitat del Sud de Calif\u00f2rnia), han publicat un llibre sobre c\u00e0ncer colorectal hereditari titulat \u201c<b>Hereditary Colorectal Cancer. Genetic Basis and Clinical Implications<\/b>\u201c.<\/span><\/span><\/span><\/p>\n<p style=\"margin:0cm 0cm 10pt\"><span style=\"font-size:11pt\"><span style=\"line-height:115%\"><span style=\"font-family:Calibri,sans-serif\">El llibre proporciona informaci\u00f3 sobre una \u00e0mplia varietat de q\u00fcestions que van des de la gen\u00e8tica fins a la descripci\u00f3 cl\u00ednica dels s\u00edndromes, les proves i l&#8217;assessorament gen\u00e8tic, i el maneig cl\u00ednic, inclosa la vigil\u00e0ncia, les intervencions quir\u00fargiques i profil\u00e0ctiques i la quimioprevenci\u00f3. Tamb\u00e9 es discuteixen temes candents actuals, com la identificaci\u00f3 de nous gens causals i els desafiaments als que ens enfrontem, aix\u00ed com la rellev\u00e0ncia dels modificadors del risc de c\u00e0ncer, tant gen\u00e8tics com ambientals. Aquest llibre de refer\u00e8ncia \u00e9s ideal per a genetistes, assessors gen\u00e8tics, onc\u00f2legs, investigadors, metges, cirurgians i infermeres, dedicats o interessats en el c\u00e0ncer hereditari. Els millors i m\u00e9s reconeguts experts en el camp de tot el m\u00f3n han contribu\u00eft a aquest projecte, garantint informaci\u00f3 actualitzada, precisi\u00f3 i discussi\u00f3 de temes d&#8217;actualitat.<\/span><\/span><\/span><\/p>\n<p style=\"margin:0cm 0cm 10pt\">\u00a0<\/p>\n<p style=\"margin-bottom:.0001pt;text-align:justify;margin:0cm 0cm 10pt\"><span style=\"font-size:11pt\"><span style=\"line-height:115%\"><span style=\"font-family:Calibri,sans-serif\">Hereditary Colorectal Cancer. Genetic Basis and Clinical Implications. Editors: Laura Valle, Stephen B. Gruber, Gabriel Capell\u00e1. Springer International Publishing. DOI: 10.1007\/978-3-319-74259-5. ISBN: 783319742595 (online); 9783319742588 (print).<\/span><\/span><\/span><\/p>\n<p style=\"margin:0cm 0cm 10pt\">\u00a0<\/p>\n<h2 style=\"margin: 0cm 0cm 10pt\">Stem Cell Genetics for Biomedical Research: Past, Present, and Future<\/h2>\n<h2 style=\"margin: 0cm 0cm 10pt\">\u00a0<\/h2>\n<p style=\"margin:0cm 0cm 10pt\">D&#8217;altra banda, el Dr. Ra\u00fcl Delgado-Morales, investigador i actual adjunt a la direcci\u00f3n cient\u00edfica de l&#8217;IDIBELL, acaba de publicar &#8221; Stem Cell Genetics for Biomedical Research: Past, Present, and Future&#8221; com a editor. El llibre analitza l\u2019estat actualde la tecnologia en c\u00e8l\u00b7lules i el seu rol fonamental per avan\u00e7ar en el camp de la modelitzaci\u00f3 de malalties i el trasplantament cel\u00b7lular. Centrant-se en casos com la malaltia d&#8217;Alzheimer, el c\u00e0ncer i els trastorns card\u00edacs, el llibre resumeix les principals troballes en el camp de les c\u00e8l\u00b7lules mare humanes i exposa les limitacions actuals sobre la nostra comprensi\u00f3 de la biologia de c\u00e8l\u00b7lules mare. Els cap\u00edtols se centren en la gen\u00e8tica, la gen\u00f2mica, l&#8217;epigen\u00e8tica i la fisiologia dels models de c\u00e8l\u00b7lules mare, juntament amb els aven\u00e7os tecnol\u00f2gics en biologia molecular com CRISPR\/Cas9 o l&#8217;edici\u00f3 epigen\u00e8tica, que seran fonamentals en el modelatge i tractament de malalties humanes.<\/p>\n<p style=\"margin:0cm 0cm 10pt\">A partir de les limitacions dels models actuals de malaltia i davant la necessitat insatisfeta de trobar intervencions terap\u00e8utiques per a trastorns humans, la disponibilitat de tecnologia de c\u00e8l\u00b7lules mare ha obert noves portes a diversos \u00e0mbits. La capacitat d&#8217;auto-renovaci\u00f3 il\u00b7limitada i el potencial de diferenciaci\u00f3 m\u00e9s extens de les c\u00e8l\u00b7lules mare constitueix una font inesgotable de qualsevol subtipus cel\u00b7lular. Des que el professor Shinya Yamanaka va descriure, fa deu anys, que les c\u00e8l\u00b7lules som\u00e0tiques podrien reprogramar-se a c\u00e8l\u00b7lules mare indu\u00efbles (iPSC) nom\u00e9s expressant quatre factors de transcripci\u00f3, el camp ha explotat, especialment les seves aplicacions en recerca biom\u00e8dica.\u00a0<br \/>\u00a0<\/p>\n<p style=\"margin:0cm 0cm 10pt\">Stem Cell Genetics for Biomedical Research: Past, Present, and Future. Editor: Raul Delgado-Morales.\u00a0Springer International Publishing. ISBN 978-3-319-90695-9<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hereditary Colorectal Cancer. Genetic Basis and Clinical Implications Els Drs Laura Valle i Gabriel Capell\u00e1, investigadors del Programa de C\u00e0ncer Hereditari de l&#8217;Institut Catal\u00e0 d&#8217;Oncologia, IDIBELL (Oncobell), al costat del Dr. Stephen B. Gruber, del Norris Comprehensive Cancer Center (Universitat del Sud de Calif\u00f2rnia), han publicat un llibre sobre c\u00e0ncer colorectal hereditari titulat \u201cHereditary Colorectal [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[417,376],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-10 11:32:39","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/7613"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=7613"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/7613\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=7613"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=7613"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=7613"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}