La investigadora de l’IDIBELL – Universitat de Barcelona Ruth Rodr\u00edguez Barrueco ha estat guardonada amb un dels cinc Premis d’Investigaci\u00f3 L’Or\u00e9al-UNESCO “For women in science\u201d en la seva convocat\u00f2ria 2018-2019. El premi, dotat amb 15.000 euros, donar\u00e0 suport i promour\u00e0 el projecte dut a terme per la Dra. Rodr\u00edguez-Barrueco, que se centra en el descobriment de noves dianes terap\u00e8utiques per al tractament del c\u00e0ncer de mama.<\/p>\n
\u00a0<\/p>\n
El c\u00e0ncer de mama \u00e9s la causa m\u00e9s comuna de mort per c\u00e0ncer femen\u00ed a Europa; \u00e9s encara necessari cercar tractaments efectius per als casos m\u00e9s agressius. S’ha descrit una petita poblaci\u00f3 de c\u00e8l\u00b7lules que presenten caracter\u00edstiques de c\u00e8l\u00b7lules mare en c\u00e0ncer de mama (breast cancer stem cells, BCSC) que es relacionada amb la progressi\u00f3 tumoral, la resist\u00e8ncia al tractament i la met\u00e0stasi. Nous enfocaments terap\u00e8utics proposen l’\u00fas d’agents dirigits a aquestes c\u00e8l\u00b7lules mare en combinaci\u00f3 amb la quimioter\u00e0pia tradicional. No obstant aix\u00f2, l’eliminaci\u00f3 selectiva de BCSC segueix sent un repte, ja que s\u00f3n molt similars a les c\u00e8l\u00b7lules mare normals.<\/p>\n
\u00a0<\/p>\n
“En aquest projecte, proposem desenvolupar una estrat\u00e8gia per identificar alguns dels mecanismes moleculars essencials perqu\u00e8 les BCSC sobrevisquin. Per a aix\u00f2, utilitzarem la llibreria de CRISPRs que hem generat en el nostre laboratori recentment. La identificaci\u00f3 i validaci\u00f3 de vulnerabilitats espec\u00edfiques de BCSC t\u00e9 importants implicacions cl\u00edniques ja que poden representar candidats efectius per a noves ter\u00e0pies dirigides”, explica la investigadora de l’IDIBELL.<\/p>\n
\u00a0<\/p>\n
La investigaci\u00f3 pr\u00e8via de la Dra. Rodr\u00edguez Barrueco, duta a terme durant un postdoctorat de sis anys a la Universitat de Columbia i l’Escola de Medicina Mount Sinai (Nova York), va tenir un enfocament traslacional. El 2016 es va unir a la Universitat de Newcastle com Faculty Fellow; tamb\u00e9 va rebre una beca Marie Sklodowska-Curie finan\u00e7ada pel programa H2020 de la Uni\u00f3 Europea. Aquest 2018, la investigadora s\u2019ha incorporat a l’IDIBELL com a investigadora Ramon y Cajal.\u00a0Recentment, tamb\u00e9 ha estat distingida amb\u00a0una de les quatre beques anuals de l’Asociaci\u00f3n Espa\u00f1ola de Investigaci\u00f3n sobre el C\u00e1ncer\u00a0(ASEICA) . L’ajut,\u00a0entregat el passat 8 de novembre en el marc del\u00a016\u00e8 Congr\u00e9s Internacional de\u00a0l’Associaci\u00f3, va recon\u00e8ixer\u00a0“els treballs m\u00e9s punters d’investigadors joves i tamb\u00e9 d’aquells que compten amb una traject\u00f2ria destacable”.<\/p>\n
\u00a0<\/p>\n
La iniciativa L’Or\u00e9al-UNESCO per a les dones en la ci\u00e8ncia, creada el 1998 per la Fundaci\u00f3 L’Or\u00e9al i la UNESCO (Organitzaci\u00f3 de les Nacions Unides per a l’Educaci\u00f3, la Ci\u00e8ncia i la Cultura) t\u00e9 com a objectiu recon\u00e8ixer les investigadores que, a trav\u00e9s de l’abast del seu treball, contribueixen a superar els desafiaments globals actuals. A dia d\u2019avui, el t\u00e0ndem L’Or\u00e9al-UNESCO ha distingit a 97 dones eminents en l’apogeu de les seves carreres cient\u00edfiques i ha donat suport a 2698 dones cient\u00edfiques prometedores a trav\u00e9s de beques de doctorat i postdoctorat. En total, m\u00e9s de 2795 dones han estat reconegudes en m\u00e9s de 115 pa\u00efsos.<\/p>\n
\u00a0<\/p>\n
Les dones segueixen estant insuficientment representades en la vida p\u00fablica i professional, particularment en ci\u00e8ncies, on el “sostre de vidre” encara \u00e9s una realitat. Avui, nom\u00e9s el 28% dels cient\u00edfics s\u00f3n dones i nom\u00e9s el 3% dels premis Nobel de ci\u00e8ncies s’han atorgat a dones des que van comen\u00e7ar el 1901. Tot i aix\u00f2, hi ha moltes cient\u00edfiques eminents, i elevar el seu perfil \u00e9s vital per promoure una major igualtat de g\u00e8nere en la ci\u00e8ncia.<\/p>\n
\u00a0<\/p>\n
\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"
La investigadora de l’IDIBELL – Universitat de Barcelona Ruth Rodr\u00edguez Barrueco ha estat guardonada amb un dels cinc Premis d’Investigaci\u00f3 L’Or\u00e9al-UNESCO “For women in science\u201d en la seva convocat\u00f2ria 2018-2019. El premi, dotat amb 15.000 euros, donar\u00e0 suport i promour\u00e0 el projecte dut a terme per la Dra. Rodr\u00edguez-Barrueco, que se centra en el descobriment […]<\/p>\n","protected":false},"author":6,"featured_media":10520,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[332,365],"tags":[],"class_list":["post-7536","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","category-cancer-ginecologic"],"publishpress_future_action":{"enabled":false,"date":"2024-11-29 03:37:45","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/7536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=7536"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/7536\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/10520"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=7536"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=7536"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=7536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}