Investigadores del grup de recerca en Cognici\u00f3 i Plasticitat Cerebral de l’Institut d’Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL) i la Universitat de Barcelona (UB), en col\u00b7laboraci\u00f3 amb diversos hospitals, han descobert que un estil de vida intel\u00b7lectualment actiu confereix protecci\u00f3 enfront de la neurodegeneraci\u00f3 en persones amb malaltia d’Huntington, retardant l’aparici\u00f3 de s\u00edmptomes i de p\u00e8rdua de subst\u00e0ncia grisa al cervell. La investigaci\u00f3, liderada per la Dra. Estela C\u00e0mara i la investigadora de doctorat Clara Garc\u00eda Gorro, contribueix a entendre els factors relacionats amb les difer\u00e8ncies de s\u00edmptomes entre pacients amb aquesta malaltia i a desxifrar els mecanismes cerebrals responsables de tals difer\u00e8ncies.<\/p>\n
\u00a0<\/p>\n
L’estudi, publicat a Neuropsychologia, demostra com els pacients amb malaltia de Huntington amb major activitat cognitiva al llarg de la vida obtenen millors puntuacions en proves neuropsicol\u00f2giques. “Aquests pacients van mostrar un retard en l’aparici\u00f3 dels primers s\u00edmptomes de la malaltia i un menor nivell d’atr\u00f2fia en una zona del cervell especialment afectada en aquesta malaltia, el nucli caudat”, explica Clara Garc\u00eda Gorro.<\/p>\n
\u00a0<\/p>\n
Per avaluar l’activitat intel\u00b7lectual al llarg de la vida, es va tenir en compte el nivell educatiu, el tipus d’ocupaci\u00f3 professional, el nombre d’idiomes, l’activitat lectora i la freq\u00fc\u00e8ncia amb qu\u00e8 els participants jugaven a jocs com els escacs, entre altres factors.
Aquests resultats suggereixen que una major activitat mental protegeix a cert nivell al cervell del proc\u00e9s neurodegeneratiu, mantenint-lo en bon estat m\u00e9s temps. “Per tant, aquest descobriment recalca la import\u00e0ncia de les intervencions cognitives en malalties neurodegeneratives i de portar una vida cognitivament estimulant per mantenir un cervell sa”, afegeix la Dra. C\u00e1mara.<\/p>\n
\u00a0<\/p>\n
La malaltia de Huntington \u00e9s una malaltia neurodegenerativa d’origen gen\u00e8tic per a la qual no existeix cura actualment. Els seus principals s\u00edmptomes inclouen problemes motors, cognitius i psiqui\u00e0trics. L’edat mitjana d’aparici\u00f3 dels primers s\u00edmptomes \u00e9s al voltant dels 40 anys, sent una malaltia progressiva en la qual els s\u00edmptomes empitjoren gradualment.
\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"
El descobriment recalca la import\u00e0ncia de portar una vida cognitivament estimulant per mantenir un cervell sa<\/p>\n","protected":false},"author":6,"featured_media":10518,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[368,340],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-11 16:38:28","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/7531"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=7531"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/7531\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/10518"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=7531"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=7531"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=7531"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}