L\u2019empresa nanobiotecnol\u00f2gica Paperdrop Diagnostics, spinoff de l\u2019Institut Catal\u00e0 de Nanoci\u00e8ncia i Nanotecnologia (ICN2), ha iniciat el desenvolupament de l\u2019ISR-TEST, el primer dispositiu que permet identificar els pacients amb risc de patir malalties isqu\u00e8miques.\u00a0<\/p>\n
El test es desenvolupa en base a l\u2019an\u00e0lisi d\u2019un biomarcador espec\u00edfic per predir el risc d’accident vascular cerebral isqu\u00e8mic primari i secundari patentat per l\u2019Institut d\u2019Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL) i l\u2019Hospital Universitari M\u00fatuaTerrassa. \u201cAquest biomarcador es un \u00e0cid nucleic petit circulant la concentraci\u00f3 del qual es troba alterada en la sang dels pacients amb alt risc o que han patit recentment un ictus isqu\u00e8mic\u201d, assenyala el Dr. Josep M. Aran, cap del grup \u00a0de recerca en processos immunoinflamatoris i ter\u00e0pia g\u00e8nica de l\u2019IDIBELL.\u00a0<\/p>\n
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La proposta de Paperdrop Diagnostics \u00e9s la implementaci\u00f3 d\u2019aquest biomarcador sobre un dispositiu anal\u00edtic basat en microflu\u00eddica en paper i en la tecnologia de flux lateral, similars a un test d\u2019embar\u00e0s.\u00a0<\/p>\n
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\u201cEs tracta d\u2019una soluci\u00f3 de baix cost i f\u00e0cil d’utilitzar que requereix tan sols d\u2019un sensor de paper i una gota de sang del pacient per fer-ne el diagn\u00f2stic, convertint-se aix\u00ed en una eina de pron\u00f2stic crucial per als professionals, ja que permetr\u00e0 prioritzar les intervencions, reduir les discapacitats i dissenyar la millor l\u2019estrat\u00e8gia terap\u00e8utica per a cada pacient\u201d, explica el Dr. Marc Gallegos, CEO de l\u2019empresa. A m\u00e9s a m\u00e9s, la senzillesa, i la rapidesa de l\u2019ISR-TEST pot suposar una reducci\u00f3 de la pressi\u00f3 assistencial a les consultes de metges especialistes, derivant la valoraci\u00f3 i la monitoritzaci\u00f3 de la malaltia als Centres d\u2019Atenci\u00f3 Prim\u00e0ria.\u00a0<\/p>\n
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L\u2019ictus cerebral \u00e9s una malaltia greu que anualment afecta a 15 milions de persones al m\u00f3n, segons l’Organitzaci\u00f3 Mundial de la Salut (OMS). Gaireb\u00e9 el 85% dels ictus s\u00f3n els anomenats isqu\u00e8mics, provocats per l\u2019estrenyiment o la constricci\u00f3 de l\u2019art\u00e8ria car\u00f2tida. La situaci\u00f3 de baix aflux sanguini causada per la isqu\u00e8mia pot acabar produint lesions cerebrals irreversibles. \u201cLa detecci\u00f3 preco\u00e7 i identificaci\u00f3 dels pacients amb alt risc de tenir ictus seria una eina extraordin\u00e0ria per reduir l\u2019impacte d’aquesta malaltia a la societat. A m\u00e9s, el fet de disposar d’un biomarcador secundari que pugui identificar un risc elevat de recurr\u00e8ncia d’ictus podria ajudar a optimitzar els tractaments de prevenci\u00f3 secund\u00e0ria\u201d, comenta el Dr. Jerzy Krupinski, cap del servei de Neurologia de l\u2019Hospital Universitari M\u00fatuaTerrassa.<\/p>\n
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En l\u2019actualitat, el diagn\u00f2stic preco\u00e7 de l\u2019ictus isqu\u00e8mic, sobretot en pacients no simptom\u00e0tics, \u00e9s gaireb\u00e9 inexistent. Les solucions diagn\u00f2stiques disponibles nom\u00e9s s\u00f3n \u00fatils despr\u00e9s que es manifesti la simptomatologia, mentre que les solucions predictives basades en t\u00e8cniques d’imatge (ecografia, tomografia, resson\u00e0ncia magn\u00e8tica) suposen elevats costos pels hospitals i tenen una menor sensibilitat.<\/p>\n
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El projecte est\u00e0 tutelat pel Prof. ICREA Arben Merko\u00e7i, fundador de Paperdrop Diagnostics i investigador principal del Grup de Nanobioelectr\u00f2nica i Biosensors de l\u2019Institut Catal\u00e0 de Nanoci\u00e8ncia i Nanotecnologia (ICN2), juntament amb la direcci\u00f3 del Dr. Daniel Quesada, responsable de la part tecnol\u00f2gica de l\u2019empresa. En l\u2019\u00e0mbit cl\u00ednic, el projecte est\u00e0 liderat pel Dr. Jerzy Krupinski i pel Dr. Josep Maria Aran.<\/p>\n
\u00a0<\/p>\n
L\u2019empresa, ubicada al Parc de Recerca UAB, ha participat a l\u2019\u00faltima edici\u00f3 del programa Empenta d\u2019Esadecreapolis i ACCI\u00d3 i compta amb el suport del Ministeri de Ci\u00e8ncia, Innovaci\u00f3 i Universitats que finan\u00e7a el seu desenvolupament a trav\u00e9s del programa Retos de Colaboraci\u00f3n 2017.
\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"
L\u2019objectiu de l\u2019acord \u00e9s desenvolupar un test diagn\u00f2stic de baix cost capa\u00e7 de valorar el risc d\u2019ictus isqu\u00e8mic en pacients sense simptomatologia<\/p>\n","protected":false},"author":6,"featured_media":7512,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[334,378],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-04 22:29:05","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/7511"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=7511"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/7511\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/7512"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=7511"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=7511"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=7511"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}