{"id":26169,"date":"2024-07-25T10:07:37","date_gmt":"2024-07-25T08:07:37","guid":{"rendered":"https:\/\/idibell.cat\/?p=26169"},"modified":"2024-07-25T10:07:37","modified_gmt":"2024-07-25T08:07:37","slug":"els-serveis-cientificotecnics-de-lidibell-incorporen-una-nova-plataforma-de-transcriptomica-i-proteomica-espacial","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2024\/07\/els-serveis-cientificotecnics-de-lidibell-incorporen-una-nova-plataforma-de-transcriptomica-i-proteomica-espacial\/","title":{"rendered":"Els serveis cientificot\u00e8cnics de l\u2019IDIBELL incorporen una nova plataforma de transcript\u00f2mica i prote\u00f2mica espacial"},"content":{"rendered":"<p>L\u2019IDIBELL ha incorporat una nova plataforma de transcript\u00f2mica i prote\u00f2mica espacial d\u2019alta resoluci\u00f3 al laboratori d\u2019Interaccions moleculars dels seus serveis cientificot\u00e8cnics. L\u2019operaci\u00f3 ha estat possible gr\u00e0cies a la consecuci\u00f3 d\u2019un ajut corresponent a la convocat\u00f2ria <em>IFEQ22 Adquisici\u00f3n de Equipamiento e Infraestructuras cient\u00edfico-t\u00e9cnicas <\/em>de l\u2019ISCIII.<\/p>\n<p>La plataforma de tanscript\u00f2mica i prote\u00f2mica espacial d&#8217;alta resoluci\u00f3 CosMx (Nanostring, prove\u00efdor Longwood) permet visualitzar i quantificar de manera precisa l&#8217;expressi\u00f3 d&#8217;ARNs i prote\u00efnes amb resoluci\u00f3 de \u201csingle cell\u201d (\u00e9s a dir, d\u2019un \u00fanica c\u00e8l\u00b7lula) en seccions de teixit de diferents tipus de mostra. Est\u00e0 basada en la tecnologia d&#8217;hibridaci\u00f3 <em>in situ<\/em> altament sensible i amb alta capacitat de multiplexat per a l&#8217;estudi de l&#8217;expressi\u00f3 de gens i prote\u00efnes.<\/p>\n<p>El nou equipament identifica i quantifica biomarcadors tant a nivell d&#8217;ARN com prote\u00efna\u00a0 relacionant i visualitzant l&#8217;expressi\u00f3 a nivell cel\u00b7lular amb la distribuci\u00f3 espacial en el teixit histol\u00f2gic, objecte d&#8217;estudi de diferents malalties. Aix\u00f2 permetr\u00e0 identificar i localitzar m\u00faltiples tipus cel\u00b7lulars amb les caracter\u00edstiques fenot\u00edpiques i funcionals, aix\u00ed com les estructures extracel\u00b7lulars associades i generar una informaci\u00f3 completa del microambient tissular.<\/p>\n<p>L&#8217;equipament est\u00e0 finan\u00e7at per l&#8217;Instituto de Salud Carlos III a c\u00e0rrec dels fons europeus del Pla de Recuperaci\u00f3, Transformaci\u00f3 i Resili\u00e8ncia, amb codi d&#8217;expedient IFEQ22\/00027, finan\u00e7at per la Uni\u00f3 Europea \u2013 NextGenerationEU.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-26172\" src=\"https:\/\/idibell.cat\/wp-content\/uploads\/2024\/07\/Logos-plataforma-proteomica.png\" alt=\"\" width=\"428\" height=\"177\" srcset=\"https:\/\/idibell.cat\/wp-content\/uploads\/2024\/07\/Logos-plataforma-proteomica.png 1441w, https:\/\/idibell.cat\/wp-content\/uploads\/2024\/07\/Logos-plataforma-proteomica-300x124.png 300w, https:\/\/idibell.cat\/wp-content\/uploads\/2024\/07\/Logos-plataforma-proteomica-1024x424.png 1024w, https:\/\/idibell.cat\/wp-content\/uploads\/2024\/07\/Logos-plataforma-proteomica-768x318.png 768w\" sizes=\"(max-width: 428px) 100vw, 428px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><em>L\u2019Institut d\u2019Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL) \u00e9s un centre de recerca en biomedicina creat l\u2019any 2004. Est\u00e0 participat per l\u2019Hospital Universitari de Bellvitge i l\u2019Hospital de Viladecans de l\u2019Institut Catal\u00e0 de la Salut, l\u2019Institut Catal\u00e0 d\u2019Oncologia, la Universitat de Barcelona i l\u2019Ajuntament de l\u2019Hospitalet de Llobregat.<\/em><\/p>\n<p><em>L\u2019IDIBELL \u00e9s membre del Campus d\u2019Excel\u00b7l\u00e8ncia Internacional de la Universitat de Barcelona HUBc i forma part de la instituci\u00f3 CERCA de la Generalitat de Catalunya. L\u2019any 2009 es va convertir en un dels cinc primers centres d\u2019investigaci\u00f3 espanyols acreditats com a institut d\u2019investigaci\u00f3 sanit\u00e0ria per l\u2019Instituto de Salud Carlos III. A m\u00e9s, forma part del programa \u201cHR Excellence in Research\u201d de la Uni\u00f3 Europea i \u00e9s membre de EATRIS i REGIC. Des de l\u2019any 2018, l\u2019IDIBELL \u00e9s un Centro Acreditado de la Fundaci\u00f3n Cient\u00edfica AECC (FCAECC).<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>La compra de l\u2019equipament ha estat finan\u00e7ada per l&#8217;Instituto de Salud Carlos III (convocat\u00f2ria IFEQ22)<\/p>\n","protected":false},"author":8,"featured_media":26170,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-26169","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sin-categorizar"],"publishpress_future_action":{"enabled":false,"date":"2024-11-11 20:20:55","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/26169"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=26169"}],"version-history":[{"count":3,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/26169\/revisions"}],"predecessor-version":[{"id":26175,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/26169\/revisions\/26175"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/26170"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=26169"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=26169"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=26169"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}