{"id":26111,"date":"2024-07-09T16:47:18","date_gmt":"2024-07-09T14:47:18","guid":{"rendered":"https:\/\/idibell.cat\/?p=26111"},"modified":"2024-07-09T16:47:18","modified_gmt":"2024-07-09T14:47:18","slug":"la-fundacion-mutua-madrilena-dona-suport-a-un-projecte-de-bellvitge-que-impulsara-lus-clinic-de-ronyons-bioartificials","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2024\/07\/la-fundacion-mutua-madrilena-dona-suport-a-un-projecte-de-bellvitge-que-impulsara-lus-clinic-de-ronyons-bioartificials\/","title":{"rendered":"La Fundaci\u00f3n Mutua Madrile\u00f1a dona suport a un projecte de Bellvitge que impulsar\u00e0 l’\u00fas cl\u00ednic de ronyons bioartificials"},"content":{"rendered":"

Avui, la Fundaci\u00f3n Mutua Madrile\u00f1a va lliurar les Ajudes a la Recerca en Salut. En aquesta vint-i-unena edici\u00f3, la Fundaci\u00f3 va donar suport al treball de 18 instituts d’investigaci\u00f3 i hospitals a tot Espanya. Els projectes han estat seleccionats pel comit\u00e8 cient\u00edfic de la Fundaci\u00f3 en \u00e0rees clau com la immunoter\u00e0pia del c\u00e0ncer, immunotoler\u00e0ncia dels trasplantaments, \u00f2rgans bioartificials, traumatologia, malalties rares infantils i la salut mental dels joves.<\/p>\n

El Dr. Miguel Hueso, investigador principal del grup de recerca en Nefrologia i trasplantament renal<\/a> de\u00a0 l’IDIBELL i nefr\u00f2leg de l’Hospital Universitari de Bellvitge, ha estat un dels beneficiaris en la categoria d’\u00f2rgans bioartificials pel seu projecte “Sinergia BioDigital: impuls per a l’\u00fas cl\u00ednic de Ronyons Bioartificials integrant \u00d2rgans-on-Chip, models computacionals i bessons digitals”.<\/p>\n

Aquesta iniciativa col\u00b7laborativa involucra equips de cinc centres de recerca espanyols que treballaran conjuntament per desenvolupar models experimentals i computacionals del rony\u00f3, aquests \u00faltims coneguts com a bessons digitals. L’objectiu d’aquest estudi \u00e9s disposar d’eines que donin suport a les decisions cl\u00edniques, accelerin el desenvolupament de nous f\u00e0rmacs, i contribueixin al desenvolupament d\u2019\u00f2rgans bioartificials.<\/p>\n

\"\"Els investigadors crearan primer un rony\u00f3-on-a-chip, un dispositiu miniaturitzat que replica la funci\u00f3 de l’\u00f2rgan hum\u00e0 al laboratori. D’aquesta manera, ser\u00e0 possible estudiar malalties i provar medicaments de manera r\u00e0pida, flexible i eficient. Es tracta de plataformes microflu\u00eddiques que simulen la complexitat i el comportament dels \u00f2rgans, superant els cultius cel\u00b7lulars tradicionals i els models animals.<\/p>\n

Gr\u00e0cies a aquesta plataforma, es podr\u00e0, per exemple, estudiar la viabilitat de les c\u00e8l\u00b7lules i la seva capacitat de detoxificaci\u00f3 de la sang i concentraci\u00f3 de fluids. Amb les dades obtingudes, es preparar\u00e0 un bess\u00f3 digital del rony\u00f3 que combinar\u00e0 la precisi\u00f3 de la bioenginyeria amb les \u00faltimes innovacions en inform\u00e0tica i realitat virtual.<\/p>\n

Aquestes tecnologies resultaran de gran utilitat per personalitzar els tractaments m\u00e8dics, ajustant les ter\u00e0pies a les necessitats espec\u00edfiques de cada pacient. Tamb\u00e9 serviran per avaluar l’efic\u00e0cia i seguretat de nous f\u00e0rmacs abans d’administrar-los a persones, millorant la precisi\u00f3 en els assaigs cl\u00ednics i agilitant el proc\u00e9s de desenvolupament de f\u00e0rmacs.<\/p>\n

Finalment, es far\u00e0 servir tot el coneixement generat i la impressi\u00f3 3D de c\u00e8l\u00b7lules per crear un dispositiu que pugui ser utilitzat com a \u00f2rgan bioartificial. A llarg termini, s’espera que aquestes eines fetes amb materials biocompatibles i tecnologia avan\u00e7ada redueixin la depend\u00e8ncia de la donaci\u00f3 d’\u00f2rgans i dels equips de di\u00e0lisi per a persones amb malalties renals cr\u00f2niques.<\/p>\n

A m\u00e9s d’investigadors de l’IDIBELL i l’Hospital Universitari de Bellvitge, en el consorci hi participen professionals de l’Hospital Universitari La Paz de Madrid, l’Institut d’Investigaci\u00f3 Sanit\u00e0ria Arag\u00f3, la Fundaci\u00f3 per a la Investigaci\u00f3 M\u00e8dica Aplicada de Navarra, i la Universitat d’Extremadura.<\/p>\n","protected":false},"excerpt":{"rendered":"

L’estudi, liderat pel Dr. Miguel Hueso, ajudar\u00e0 a crear alternatives a la donaci\u00f3 d’\u00f2rgans i la di\u00e0lisi per al tractament de malalties cr\u00f2niques, i al desenvolupament de nous f\u00e0rmacs.<\/p>\n","protected":false},"author":8,"featured_media":26112,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-26111","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sin-categorizar"],"publishpress_future_action":{"enabled":false,"date":"2024-12-29 20:10:57","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/26111","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=26111"}],"version-history":[{"count":1,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/26111\/revisions"}],"predecessor-version":[{"id":26114,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/26111\/revisions\/26114"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/26112"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=26111"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=26111"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=26111"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}