{"id":26104,"date":"2024-07-05T09:45:54","date_gmt":"2024-07-05T07:45:54","guid":{"rendered":"https:\/\/idibell.cat\/?p=26104"},"modified":"2024-07-05T09:45:54","modified_gmt":"2024-07-05T07:45:54","slug":"bellvitge-contribueix-a-una-millora-significativa-en-el-tractament-de-langioedema-hereditari","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2024\/07\/bellvitge-contribueix-a-una-millora-significativa-en-el-tractament-de-langioedema-hereditari\/","title":{"rendered":"Bellvitge contribueix a una millora significativa en el tractament de l\u2019angioedema hereditari"},"content":{"rendered":"

Investigadors de l’Hospital Universitari de Bellvitge (HUB) i l\u2019IDIBELL han participat en un assaig cl\u00ednic que ha demostrat l’efic\u00e0cia del sebetralstat, un nou tractament oral per als atacs d’angioedema hereditari (HAE). Publicat a The New England Journal of Medicine<\/em><\/a>, els resultats d\u2019aquest estudi, en el qual han participat dos pacients de l\u2019HUB, s\u00f3n el primer aven\u00e7 en una d\u00e8cada en el tractament a demanda d\u2019aquesta malaltia.<\/p>\n

L’assaig KONFIDENT ha demostrat que aquest nou tractament proporciona un alleujament m\u00e9s r\u00e0pid dels s\u00edmptomes en comparaci\u00f3 amb el placebo, amb una resoluci\u00f3 completa dels atacs en menys temps. El medicament, que evita la necessitat d’injeccions, millorar\u00e0 significativament la qualitat de vida dels pacients amb HAE, que afecta una de cada 50.000 persones a tot el m\u00f3n.<\/p>\n

Fins ara, els tractaments per a atacs aguts d’HAE requerien administraci\u00f3 parenteral, per\u00f2 el sebetralstat, un inhibidor de la cal\u00b7licre\u00efna, transforma aquest enfocament, permetent als pacients prendre pastilles en lloc de medicaments injectables, cosa que facilita el tractament preco\u00e7 dels atacs.<\/p>\n

Segons el Dr. Ramon Lleonart, cap del Servei d\u2019Al\u00b7lergologia de l\u2019HUB i investigador de l\u2019IDIBELL que signa l\u2019article, \u201caquest tractament en pastilles comporta una gran millora de qualitat de vida, ja que actualment els pacients han de portar a sobre tractaments parenterals amb els problemes de comoditat que comporta, pel fet que els atacs s\u00f3n impredictibles i, per tant, cal que estiguin sempre preparats per un eventual atac\u201d.<\/p>\n

Centre d\u2019excel\u00b7l\u00e8ncia en HAE en l\u2019\u00e0mbit mundial<\/strong><\/p>\n

El Servei d\u2019Al\u00b7lergologia de l\u2019Hospital de Bellvitge, recentment acreditat com a centre de refer\u00e8ncia i excel\u00b7l\u00e8ncia (ACARE) en l\u2019angioedema hereditari<\/a>, ofereix una atenci\u00f3 integral als pacients amb un equip multidisciplinari format per professionals de diverses especialitats m\u00e8diques. Aquesta acreditaci\u00f3, atorgada per les xarxes GA\u00b2LEN i HAEi, reafirma el comprom\u00eds del centre en la millora de la qualitat de l\u2019atenci\u00f3 cl\u00ednica i la recerca sobre aquesta malaltia.<\/p>\n","protected":false},"excerpt":{"rendered":"

Investigadors de l’Hospital Universitari de Bellvitge (HUB) i l\u2019IDIBELL han participat en un assaig cl\u00ednic que ha demostrat l’efic\u00e0cia del sebetralstat, un nou tractament oral per als atacs d’angioedema hereditari<\/p>\n","protected":false},"author":8,"featured_media":26105,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[427,334,466],"tags":[],"class_list":["post-26104","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-malalties-sistemiques-i-envelliment","category-medicina-translacional","category-p-de-malalties-cardiovasculars-respiratories-sistemiques-i-denvelliment-cellular"],"publishpress_future_action":{"enabled":false,"date":"2024-12-29 15:14:05","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/26104","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=26104"}],"version-history":[{"count":1,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/26104\/revisions"}],"predecessor-version":[{"id":26106,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/26104\/revisions\/26106"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/26105"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=26104"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=26104"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=26104"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}