Aquesta troballa q\u00fcestiona la idea pr\u00e8via que certes lesions cerebrals eren irreversibles i obre aix\u00ed noves perspectives en el tractament de l’ictus, de forma que molts m\u00e9s pacients tindran l’opci\u00f3 de beneficiar-se dels resultats positius de la trombectomia mec\u00e0nica.<\/p>\n
<\/p>\n
A l’estudi, anomenat IN EXTREMIS-LASTE, hi han participat 26 hospitals de Fran\u00e7a i 7 d’Espanya, amb un total de 333 pacients inclosos. La investigaci\u00f3 ha estat liderada per l’Hospital Universitari de Montpeller, mentre que l’Hospital Universitari de Bellvitge \u00e9s el centre de l’estat espanyol que hi ha aportat m\u00e9s pacients.<\/p>\n
<\/p>\n
La trombectomia \u00e9s una t\u00e8cnica per restablir el flux sanguini en pacients amb ictus eliminant l’obstrucci\u00f3 amb procediments mec\u00e0nics que es va convertir en el tractament est\u00e0ndard a partir del 2015. Tanmateix, habitualment nom\u00e9s se seleccionen per a aquesta intervenci\u00f3 els pacients que nom\u00e9s pateixen quantitats limitades de dany cerebral. Aquest criteri s\u2019ha basat en la suposici\u00f3 que la restauraci\u00f3 del flux sanguini en grans \u00e0rees del cervell irreversiblement danyades no nom\u00e9s era in\u00fatil, sin\u00f3 que fins i tot podia causar danys addicionals pel major risc d’hemorr\u00e0gia, entre d\u2019altres efectes perjudicials de la reperfusi\u00f3. Tot i aix\u00f2, la xarxa internacional de centres d’ictus en la qual participa l\u2019Hospital de Bellvitge i l\u2019IDIBELL ha anat demostrant el contrari.<\/p>\n
<\/p>\n
L’assaig IN EXTREMIS-LASTE va seleccionar pacients que fins ara es consideraven \u201cirrecuperables\u201d a la pr\u00e0ctica habitual per l\u2019oclusi\u00f3 de grans vasos i els amplis danys en el teixit cerebral, els quals van ser tractats amb trombectomia mec\u00e0nica durant les 7 hores posteriors a l\u2019ictus.<\/p>\n
<\/p>\n
Les conclusions indiquen que la magnitud del benefici \u00e9s molt considerable, i similar a l\u2019observada en pacients que presentaven quantitats moderades o petites de dany cerebral. A m\u00e9s, ha estat un dels pocs assaigs de trombectomia mec\u00e0nica que han demostrat els beneficis d\u2019aquest procediment en termes de mortalitat.<\/p>\n
<\/p>\n
Del treball, se\u2019n despr\u00e8n que fins un 20% m\u00e9s de pacients amb ictus amb oclusi\u00f3 de grans vasos \u2013abans considerats inelegibles\u2013 es podran beneficiar de la trombectomia mec\u00e0nica.<\/p>\n
<\/p>\n
<\/p>\n
Segons proposen els investigadors principals de l\u2019estudi, una de les explicacions d\u2019aquests resultats pot ser que la part del cervell que els estudis d\u2019imatge suggereixen que queda morta pot ser que no ho estigui del tot. En aquestes \u00e0rees, suggereixen, hi poden quedar illes de teixit cerebral supervivents que s\u00f3n recuperables amb reperfusi\u00f3. Aquests descobriments estan en l\u00ednia amb els d\u2019altres estudis publicats recentment.<\/p>\n
<\/p>\n
Segons destaca el Dr. Pere Cardona, investigador de l\u2019IDIBELL i neur\u00f2leg de l’Hospital Universitari de Bellvitge, aquest estudi \u201cpot suposar un canvi important en els criteris de maneig de pacients amb ictus aguts amb gran oclusi\u00f3, i tamb\u00e9 obren un nou camp de recerca de models per entendre millor la mort neuronal i les capacitats de recuperaci\u00f3 del teixit cerebral en la fase aguda d\u2019un ictus\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"
Un estudi amb participaci\u00f3 de la Unitat d’Ictus de l’Hospital Universitari de Bellvitge i el grup de Malalties Neurol\u00f2giques i Neurogen\u00e8tica de l\u2019IDIBELL que ha publicat la revista cient\u00edfica The New England Journal of Medicine demostra que fins i tot els pacients d’ictus amb extenses \u00e0rees de dany cerebral es poden beneficiar de ser tractats amb trombectomia mec\u00e0nica.<\/p>\n","protected":false},"author":8,"featured_media":25604,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[416,340,457],"tags":[],"class_list":["post-25603","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-malalties-neurologiques-i-neurogenetica","category-neurociencies","category-p-de-neurociencies"],"publishpress_future_action":{"enabled":false,"date":"2024-12-25 11:42:48","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/25603","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=25603"}],"version-history":[{"count":1,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/25603\/revisions"}],"predecessor-version":[{"id":25605,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/25603\/revisions\/25605"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/25604"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=25603"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=25603"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=25603"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}