{"id":25104,"date":"2024-02-28T10:00:34","date_gmt":"2024-02-28T09:00:34","guid":{"rendered":"https:\/\/idibell.cat\/?p=25104"},"modified":"2024-02-28T15:33:13","modified_gmt":"2024-02-28T14:33:13","slug":"els-disruptors-endocrins-poden-augmentar-el-risc-de-patir-cancer-dendometri","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2024\/02\/els-disruptors-endocrins-poden-augmentar-el-risc-de-patir-cancer-dendometri\/","title":{"rendered":"Els disruptors endocrins poden augmentar el risc de patir c\u00e0ncer d\u2019endometri"},"content":{"rendered":"<p>Una investigaci\u00f3 liderada per l\u2019IDIBELL, l\u2019Institut Catal\u00e0 d\u2019Oncologia, la Universitat de Granada i l\u2019Institut d\u2019Investigaci\u00f3 Biosanit\u00e0ria de Granada, publicada avui a la revista <a href=\"https:\/\/ehp.niehs.nih.gov\/doi\/10.1289\/EHP13202\">Environmental Health Perspectives<\/a>, ha revelat la connexi\u00f3 entre contaminants ambientals i el c\u00e0ncer d\u2019endometri. Es tracta d\u2019un treball col\u00b7laboratiu en el qual han participat cient\u00edfics i metges de l\u2019Hospital Universitari de Bellvitge i del CIBERESP.<\/p>\n<p>El c\u00e0ncer d\u2019endometri \u00e9s un tipus de tumor que es desenvolupa a la cara interna de l\u2019\u00fater i suposa m\u00e9s de 5.000 nous casos a Espanya anualment, amb un gran impacte en la salut de les dones. A m\u00e9s, aquesta modalitat de c\u00e0ncer es presenta cada vegada amb major freq\u00fc\u00e8ncia, en part, per l\u2019envelliment de la poblaci\u00f3. Per altra banda, en tractar-se d\u2019un tipus de c\u00e0ncer depenent d\u2019hormones, els estr\u00f2gens poden intervenir sobre el seu desenvolupament i evoluci\u00f3.<\/p>\n<p>Aquest estudi aborda la relaci\u00f3 entre el c\u00e0ncer d\u2019endometri i l\u2019exposici\u00f3 a mescles de contaminants ambientals que poden interferir amb les funcions de les hormones. Aquesta classe de compostos, coneguts com a disruptors endocrins, actuen com a xenoestr\u00f2gens i es troben en molts productes qu\u00edmics industrials, incloent-hi pesticides i herbicides, a part de cosm\u00e8tics i altres articles de consum quotidi\u00e0.<\/p>\n<p>Mitjan\u00e7ant t\u00e8cniques avan\u00e7ades d\u2019an\u00e0lisi qu\u00edmica i assaigs biol\u00f2gics, els investigadors han avaluat la c\u00e0rrega hormonal total a la sang de m\u00e9s de 300 dones, amb c\u00e0ncer d\u2019endometri i sense. <em>\u201cL\u2019\u00fas d\u2019aquests assaigs biol\u00f2gics ens ajuda a entendre l\u2019impacte negatiu de les mescles qu\u00edmiques\u201d <\/em>afirma Marieta Fern\u00e1ndez, catedr\u00e0tica de la Universitat de Granada i investigadora de l\u2019Institut de Recerca Biosanit\u00e0ria de Granada i del CIBERESP.<\/p>\n<p>Els resultats revelen una associaci\u00f3 entre l\u2019exposici\u00f3 als disruptors endocrins i un risc m\u00e9s elevat de desenvolupar c\u00e0ncer d\u2019endometri. <em>\u201c\u00c9s interessant que trobem l\u2019efecte amb dosis mitjanes de xenoestr\u00f2gens, per\u00f2 no amb altes, de manera similar a all\u00f2 que s\u2019ha observat amb les hormones end\u00f2genes\u201d<\/em>, explica Laura Costas, investigadora de l\u2019IDIBELL i l\u2019Institut Catal\u00e0 d\u2019Oncologia.<\/p>\n<p><em>\u201cAquesta relaci\u00f3 segurament est\u00e0 vinculada amb la pr\u00f2pia naturalesa del tumor, ja que \u00e9s un c\u00e0ncer dependent d\u2019hormones. Per aix\u00f2 volem tamb\u00e9 estudiar si la pres\u00e8ncia de xenoestr\u00f2gens implicaria una pitjor evoluci\u00f3 de la patologia en aquelles dones que ja tenen la malaltia\u201d<\/em>, avan\u00e7a Costas, tamb\u00e9 investigadora del CIBERESP.<\/p>\n<p>Aquesta investigaci\u00f3 aporta llum sobre l\u2019impacte negatiu dels disruptors endocrins a la salut humana i t\u00e9 implicacions significatives per a la salut p\u00fablica. A m\u00e9s, els resultats recalquen la necessitat de considerar l\u2019efecte combinat de mescles qu\u00edmiques en el moment de l\u2019avaluaci\u00f3 del risc ambiental.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><em>L\u2019Institut d&#8217;Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL) \u00e9s un centre de recerca en biomedicina creat l\u2019any 2004. Est\u00e0 participat per l&#8217;Hospital Universitari de Bellvitge i l\u2019Hospital de Viladecans de l&#8217;Institut Catal\u00e0 de la Salut, l&#8217;Institut Catal\u00e0 d&#8217;Oncologia, la Universitat de Barcelona i l\u2019Ajuntament de l\u2019Hospitalet de Llobregat.<\/em><\/p>\n<p><em>L\u2019IDIBELL \u00e9s membre del Campus d&#8217;Excel\u00b7l\u00e8ncia Internacional de la Universitat de Barcelona HUBc i forma part de la instituci\u00f3 CERCA de la Generalitat de Catalunya. L&#8217;any 2009 es va convertir en un dels cinc primers centres d\u2019investigaci\u00f3 espanyols acreditats com a institut d\u2019investigaci\u00f3 sanit\u00e0ria per l\u2019Instituto de Salud Carlos III. A m\u00e9s, forma part del programa \u201cHR Excellence in Research\u201d de la Uni\u00f3 Europea i \u00e9s membre de EATRIS i REGIC. Des de l\u2019any 2018, l\u2019IDIBELL \u00e9s un Centro Acreditado de la Fundaci\u00f3n Cient\u00edfica AECC (FCAECC).<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Un estudi revela una associaci\u00f3 entre les mescles de contaminants ambientals i un major risc de desenvolupar c\u00e0ncer d\u2019endometri<\/p>\n","protected":false},"author":8,"featured_media":25105,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[332,337,454],"tags":[],"class_list":["post-25104","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","category-infeccions-i-cancer","category-p-depidemiologia-salut-publica-prevencio-del-cancer-i-cures-palliatives"],"publishpress_future_action":{"enabled":false,"date":"2025-03-01 20:44:16","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/25104","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=25104"}],"version-history":[{"count":3,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/25104\/revisions"}],"predecessor-version":[{"id":25120,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/25104\/revisions\/25120"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/25105"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=25104"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=25104"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=25104"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}