{"id":22292,"date":"2022-10-17T09:10:53","date_gmt":"2022-10-17T07:10:53","guid":{"rendered":"https:\/\/idibell.cat\/?p=22292"},"modified":"2022-10-17T09:11:29","modified_gmt":"2022-10-17T07:11:29","slug":"els-pacients-amb-fibrosi-pulmonar-idiopatica-que-segueixen-una-dieta-mediterrania-tenen-menys-efectes-adversos-gastrointestinals","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2022\/10\/els-pacients-amb-fibrosi-pulmonar-idiopatica-que-segueixen-una-dieta-mediterrania-tenen-menys-efectes-adversos-gastrointestinals\/","title":{"rendered":"Els pacients amb Fibrosi Pulmonar Idiop\u00e0tica que segueixen una dieta mediterr\u00e0nia tenen menys efectes adversos gastrointestinals"},"content":{"rendered":"<p>Les doctores Maria Molina i Vanesa Vicens Zygmunt han presentat en el congr\u00e9s internacional de Fibrosi els resultats de l\u2019assaig cl\u00ednic MADIET, coordinat des del grup de recerca en Pneumologia de l\u2019IDIBELL i del Hospital Universitari de Bellvitge (HUB), amb la participaci\u00f3 d\u2019hospitals de sis pa\u00efsos europeus. L\u2019<a href=\"https:\/\/www.iclaf.org\/\">International Colloquium on Lung and Airway Fibrosis 2022 (ICLAF)<\/a> s\u2019ha celebrat a Reykjav\u00edk (Isl\u00e0ndia) de l\u20191 al 5 d\u2019octubre.<\/p>\n<p>L\u2019estudi multic\u00e8ntric europeu MADIET fase IV ha demostrat que els pacients de Fibrosi Pulmonar Idiop\u00e0tica (FPI) que segueixen una dieta mediterr\u00e0nia pateixen menys efectes adversos gastrointestinals pel tractament amb pirfenidona. De fet, aquest \u00e9s un tractament habitual per als pacients amb FPI, amb una resposta positiva, tot i els efectes secundaris gastrointestinals.<\/p>\n<p>No obstant aix\u00f2, s\u2019havia observat que hi ha una menor incid\u00e8ncia en els hospitals del sud d\u2019Europa, que informen de menys efectes adversos que els pa\u00efsos del nord. Una de les raons que poden explicar aquesta difer\u00e8ncia \u00e9s la dieta. Fins ara, no s\u2019havien dut a terme estudis sobre la influ\u00e8ncia de la dieta en aquests efectes adversos.<\/p>\n<p>Aix\u00ed, doncs, amb la coordinaci\u00f3 de l\u2019IDIBELL i el HUB, s\u2019ha estudiat la dieta d\u2019uns 90 pacients d\u2019hospitals amb prescripci\u00f3 de pirfenidona. En aquest estudi multic\u00e8ntric, hi ha participat hospitals d\u2019Alemanya, Gr\u00e8cia, It\u00e0lia, Pa\u00efsos Baixos i Regne Unit, i l\u2019HUB com a representant de l\u2019Estat espanyol.<\/p>\n<p>Els participants s\u2019han dividit en dos grups: uns han seguit una dieta mediterr\u00e0nia \u2013amb abund\u00e0ncia de verdures i productes de l\u2019hort, fruita fresca, llegums i cereals, oli d\u2019oliva com a principal greix per a cuinar, peix, ingesta moderada de lactis i un baix consum de carn- i els altres una dieta rica en \u00e0cids grassos saturats durant 16 setmanes.<\/p>\n<p>Comparant els efectes gastrointestinals dels dos grups de pacients s\u2019ha comprovat que els que seguien la dieta mediterr\u00e0nia han patit significativament menys efectes adversos. A m\u00e9s, els pacients que han seguit la dieta rica en \u00e0cids grassos saturats han hagut de suspendre el tractament en un major nombre de casos.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><em>L\u2019Institut d&#8217;Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL) \u00e9s un centre de recerca en biomedicina creat l\u2019any 2004. Est\u00e0 participat per l&#8217;Hospital Universitari de Bellvitge i l\u2019Hospital de Viladecans de l&#8217;Institut Catal\u00e0 de la Salut, l&#8217;Institut Catal\u00e0 d&#8217;Oncologia, la Universitat de Barcelona i l\u2019Ajuntament de l\u2019Hospitalet de Llobregat.<\/em><\/p>\n<p><em>L\u2019IDIBELL \u00e9s membre del Campus d&#8217;Excel\u00b7l\u00e8ncia Internacional de la Universitat de Barcelona HUBc i forma part de la instituci\u00f3 CERCA de la Generalitat de Catalunya. L&#8217;any 2009 es va convertir en un dels cinc primers centres d\u2019investigaci\u00f3 espanyols acreditats com a institut d\u2019investigaci\u00f3 sanit\u00e0ria per l\u2019Instituto de Salud Carlos III. A m\u00e9s, forma part del programa \u201cHR Excellence in Research\u201d de la Uni\u00f3 Europea i \u00e9s membre de EATRIS i REGIC. Des de l\u2019any 2018, l\u2019IDIBELL \u00e9s un Centro Acreditado de la Fundaci\u00f3n Cient\u00edfica AECC (FCAECC).<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Les doctores Maria Molina i Vanesa Vicens Zygmunt han presentat en el congr\u00e9s internacional de Fibrosi els resultats de l\u2019assaig cl\u00ednic MADIET, coordinat des del grup de recerca en Pneumologia de l\u2019IDIBELL i del Hospital Universitari de Bellvitge (HUB), amb la participaci\u00f3 d\u2019hospitals de sis pa\u00efsos europeus.<\/p>\n","protected":false},"author":8,"featured_media":22293,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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