{"id":17119,"date":"2021-04-09T15:11:12","date_gmt":"2021-04-09T13:11:12","guid":{"rendered":"https:\/\/idibell.cat\/?p=17119"},"modified":"2021-04-12T08:40:19","modified_gmt":"2021-04-12T06:40:19","slug":"lanalisi-de-la-veu-amb-models-dintelligencia-artificial-pot-permetre-la-deteccio-precoc-de-lafectacio-bulbar-a-lela","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2021\/04\/lanalisi-de-la-veu-amb-models-dintelligencia-artificial-pot-permetre-la-deteccio-precoc-de-lafectacio-bulbar-a-lela\/","title":{"rendered":"L\u2019an\u00e0lisi de la veu amb models d\u2019intel\u00b7lig\u00e8ncia artificial pot permetre la detecci\u00f3 preco\u00e7 de l\u2019afectaci\u00f3 bulbar a l\u2019ELA"},"content":{"rendered":"<p>L\u2019<strong>esclerosi lateral amiotr\u00f2fica <\/strong>(ELA) \u00e9s una malaltia neurodegenerativa que es designa com a espinal quan els primers s\u00edmptomes apareixen en columna, bra\u00e7os o cames, o b\u00e9 com a bulbar quan el deteriorament de les neurones s\u2019inicia en el bulb raquidi, situat a la base del tronc encef\u00e0lic. Els s\u00edmptomes de l\u2019afectaci\u00f3 bulbar s\u00f3n problemes en la parla i la degluci\u00f3. L\u2019inici bulbar de l\u2019ELA \u00e9s minoritari en relaci\u00f3 a l\u2019espinal, per\u00f2 els pacients tenen un pron\u00f2stic pitjor. Malgrat la diferenciaci\u00f3 en la manifestaci\u00f3 dels primers s\u00edmptomes de la malaltia, un 80% dels pacients d\u2019ELA acaben experimentant problemes d\u2019articulaci\u00f3 en la parla. El deteriorament de la parla pot comen\u00e7ar fins a 3 anys abans del diagn\u00f2stic de l\u2019ELA, fet que fa fonamental la detecci\u00f3 primerenca de l\u2019afectaci\u00f3 bulbar.<\/p>\n<p>Amb aquestes premisses, l\u2019investigador del <a href=\"https:\/\/www.cimne.com\/\">CIMNE<\/a> <strong>Alberto Tena<\/strong> va comen\u00e7ar a desenvolupar aquest projecte, que parteix de l\u2019enregistrament i an\u00e0lisi ac\u00fastica de la pronunciaci\u00f3 de les 5 vocals de l\u2019alfabet per part de 45 pacients d\u2019ELA de l\u2019Hospital de Bellvitge i 18 persones de control. Amb l\u2019an\u00e0lisi ac\u00fastic de la pronunciaci\u00f3 de les vocals es van nodrir uns sistemes de <em>machine learning<\/em> (intel\u00b7lig\u00e8ncia artificial a partir d\u2019aprenentatge supervisat) que han perm\u00e8s desenvolupar uns <strong>models o marcadors de veu amb resultats molt satisfactoris<\/strong> en la identificaci\u00f3 i diferenciaci\u00f3 dels participants a l\u2019estudi amb afectaci\u00f3 bulbar, els que no la tenien i el grup de control.<\/p>\n<p>\u201c<em>Tenim molt treball per davant encara, per\u00f2 els primers resultats que hem obtingut mostren que l\u2019afectaci\u00f3 bulbar es pot detectar amb models autom\u00e0tics abans que sigui perceptible per a l\u2019o\u00efda humana, i que es poden establir mesures objectives que facilitin un diagn\u00f2stic preco\u00e7 i prec\u00eds<\/em>\u201d, destaca <strong>Alberto Tena<\/strong>. Ara per ara fins a un 10% dels pacients d\u2019ELA no s\u00f3n diagnosticats correctament de la seva afectaci\u00f3 bulbar en un primer moment.<\/p>\n<p>De la seva banda, la <strong>Dra. M\u00f2nica Povedano<\/strong>, investigadora principal del <a href=\"https:\/\/idibell.cat\/recerca\/area-de-neurociencies\/programa-de-neurociencies\/malalties-neurologiques-i-neurogenetica\/\">grup de recerca en Malalties Neurol\u00f2giques i Neurog\u00e8niques<\/a> de l\u2019IDIBELL i responsable de la Unitat Funcional de Malaltia de Motoneurona de l\u2019<a href=\"https:\/\/bellvitgehospital.cat\/ca\">Hospital de Bellvitge<\/a>, considera que la recerca obre la porta per aprofitar el gran potencial de la veu en el diagn\u00f2stic de l\u2019afectaci\u00f3 bulbar \u201c<em>i alhora demostra el valor de la integraci\u00f3 d\u2019altres disciplines en el nostre treball. En aquest cas s\u00f3n els enginyers els que ens poden ajudar en el diagn\u00f2stic de patologies neurodegeneratives<\/em>\u201d, conclou.<\/p>\n<p>La continu\u00eftat del projecte passa per ampliar la base de dades amb m\u00e9s veus i nous par\u00e0metres d\u2019an\u00e0lisi que permetin resultats m\u00e9s precisos i adre\u00e7ats a millorar la identificaci\u00f3 de l\u2019afectaci\u00f3 bulbar en els pacients d\u2019ELA. El projecte de l\u2019an\u00e0lisi de veu per aprenentatge autom\u00e0tic per a la detecci\u00f3 de l\u2019afectaci\u00f3 bulbar en pacients d\u2019ELA \u00e9s tamb\u00e9 l\u2019eix de la tesi doctoral d\u2019<strong>Alberto Tena<\/strong>, que realitza a la Universitat de Lleida (<a href=\"http:\/\/www.udl.es\/ca\/\">UdL<\/a>) sota la direcci\u00f3 dels Drs. Francesc Clari\u00e0 i Francesc Solsona. El treball, en el qual tamb\u00e9 col\u00b7labora la Universitat Tecnol\u00f2gica de Tallin (Est\u00f2nia), ha estat publicat al <a href=\"https:\/\/medinform.jmir.org\/2021\/3\/e21331\/\"><em>Journal of Medical Internet Research<\/em><\/a>.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><em>L\u2019Institut d&#8217;Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL) \u00e9s un centre de recerca en biomedicina creat l\u2019any 2004. Est\u00e0 participat per l&#8217;Hospital Universitari de Bellvitge i l\u2019Hospital de Viladecans de l&#8217;Institut Catal\u00e0 de la Salut, l&#8217;Institut Catal\u00e0 d&#8217;Oncologia, la Universitat de Barcelona i l\u2019Ajuntament de l\u2019Hospitalet de Llobregat.<\/em><\/p>\n<p><em>L\u2019IDIBELL \u00e9s membre del Campus d&#8217;Excel\u00b7l\u00e8ncia Internacional de la Universitat de Barcelona HUBc i forma part de la instituci\u00f3 CERCA de la Generalitat de Catalunya. L&#8217;any 2009 es va convertir en un dels cinc primers centres d\u2019investigaci\u00f3 espanyols acreditats com a institut d\u2019investigaci\u00f3 sanit\u00e0ria per l\u2019Instituto de Salud Carlos III. A m\u00e9s, forma part del programa \u201cHR Excellence in Research\u201d de la Uni\u00f3 Europea i \u00e9s membre de EATRIS i REGIC. Des de l\u2019any 2018, l\u2019IDIBELL \u00e9s un Centro Acreditado de la Fundaci\u00f3n Cient\u00edfica AECC (FCAECC).<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Una recerca del Centre Internacional de M\u00e8todes Num\u00e8rics a l\u2019Enginyeria (CIMNE) i la Universitat de Lleida (UdL) en la qual ha participat l\u2019IDIBELL i l\u2019Hospital de Bellvitge ha desenvolupat marcadors de veu automatitzats per identificar afectacions primerenques de la malaltia<\/p>\n","protected":false},"author":8,"featured_media":17120,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[416,340,457],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-13 19:59:09","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/17119"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=17119"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/17119\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/17120"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=17119"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=17119"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=17119"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}